Successful Treatment of Chronic Myeloproliferative Disease-unclassifiable (CMPD-U) with No Chromosomal Abnormalities by Imatinib Mesylate
スポンサーリンク
概要
- 論文の詳細を見る
We report a chronic myeloproliferative disease-unclassifiable (CMPD-U) patient who achieved hematological remission following imatinib mesylate (imatinib). Chromosomal and molecular analyses demonstrated no genetic abnormalities of c-abl, bcr-abl, c-kit or platelet-derived growth factor receptor (PDGFR) genes from hematopoietic cells. Although there has been one report of CMPD-U patient with chromosomal abnormalities of the PDGFR gene having complete hematologic responses upon treatment with imatinib, there have not been similar reports of patients without chromosomal abnormalities. This is the first case report of a CMPD-U patient with no chromosomal abnormalities who completely responded to treatment with imatinib.
著者
-
Kobune Masayoshi
The Fourth Department of Internal Medicine Sapporo Medical University
-
Takimoto Rishu
The Fourth Department of Internal Medicine Sapporo Medical University
-
Matsunaga Takuya
The Fourth Department of Internal Medicine Sapporo Medical University
-
TAKAYAMA Tetsuji
The Fourth Department of Internal Medicine, Sapporo Medical University School of Medicine
-
SATO Tsutomu
The Fourth Department of Internal Medicine, Sapporo Medical University, School of Medicine
-
NIITSU Yoshiro
the Fourth Department of Internal Medicine Sapporo Medical College
-
Araki Naoko
The Fourth Department of Internal Medicine, Sapporo Medical University, School of Medicine
-
Iyama Satoshi
The Fourth Department of Internal Medicine, Sapporo Medical University School of Medicine
-
Murase Kazuyuki
The Fourth Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan
-
Takayama Tetsuji
The Fourth Department of Internal Medicine, Sapporo Medical University, School of Medicine
-
Sagawa Tamotsu
The Fourth Department of Internal Medicine, Sapporo Medical University, School of Medicine
-
KOBUNE Masayoshi
the Fourth Department of Internal Medicine Sapporo Medical College
関連論文
- Pure Red Cell Aplasia Associated with Goods Syndrome Accompanied by Decreased Stem Cell Factor Production in the Bone Marrow
- Late Onset Neutropenia and Immunoglobulin Suppression of the Patients with Malignant Lymphoma Following Autologous Stem Cell Transplantation with Rituximab
- Enhanced Expression of Type IV Collagen-binding Protein (p29) in Fyn-transfected Murine Fibrosarcoma Cells
- Successful Treatment of Chronic Myeloproliferative Disease-unclassifiable (CMPD-U) with No Chromosomal Abnormalities by Imatinib Mesylate
- Systemic Lupus Erythematosus with a Giant Rectal Ulcer and Perforation
- Successful Treatment of Autoimmune Pancreatitis Complicated with Autoimmune Thrombocytopenia and Interstitial Pneumonia by Prednisolone
- Successful Treatment by Fibrin Glue Sealant for Pneumothorax with Chronic GVHD Resistant to Autologous Blood Patch Pleurodesis
- Ectopic Choroidal Calcification of the Eyes of a Patient with Parathyroid Adenoma.