Mental Retardation and Lifetime Events of Duchenne Muscular Dystrophy in Japan
スポンサーリンク
概要
- 論文の詳細を見る
Objective This study investigated the relationship between mental retardation and lifetime events in patients with Duchenne muscular dystrophy (DMD). Methods The data on mental retardation and ages of lifetime events (first walking, loss of ambulation, introductions of ventilator support and tube nutrition and death) were collected retrospectively, and the relationships between the factors were analyzed. Patients Among 194 DMD patients admitted to our hospital between 1995 and 2007, 74 patients underwent evaluation of their intelligence quotient (IQ). Results Twenty-eight patients (38%) demonstrated mental retardation (IQ<70). DMD patients with mental retardation started walking later, required ventilator and tube nutrition support earlier, and died earlier than those without mental retardation. Conclusions Since the prognosis of DMD patients with mental retardation was worse than that of those without mental retardation, more careful treatment is necessary for DMD patients with mental retardation.
著者
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Tamura Takuhisa
Department of Internal Medicine, National Hospital Organization Higashi-Saitama National Hospital
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Kawai Mitsuru
Department of Neurology, National Hospital Organization Higashi-Saitama National Hospital
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Mochizuki Hitoshi
Department of Neurology, Higashi-Saitama National Hospital
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Miyatake Satoko
Department of Neurology, Higashi-Saitama National Hospital
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Suzuki Mikiya
Department of Neurology, Higashi-Saitama National Hospital
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Shigeyama Toshiki
Department of Cardiology, Higashi-Saitama National Hospital
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Yatabe Kana
Department of Neurology, Higashi-Saitama National Hospital
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Ogata Katsuhisa
Department of Neurology, Higashi-Saitama National Hospital
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Suzuki Mikiya
Department Of Neurology Sapporo Medical University School Of Medicine
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Ogata Katsuhisa
Department Of Neurology Graduate School Of Medicine The University Of Tokyo
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Tamura Takuhisa
Department Of Internal Medicine National Sanatorium Kawatana Hospital
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Miyatake Satoko
Department Of Human Genetics Nagasaki University School Of Medicine
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Mochizuki Hitoshi
Department Of Communication Systems Faculty Of Electro-communications The University Of Electro-comm
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Kawai Mitsuru
Department of Neurology, Higashi-Saitama National Hospital
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MOCHIZUKI Hitoshi
Department of Agricultural Chemistry, Faculty of Agriculture, Hokkaido University
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