Clinical Relevance of Sputum Cytology and Chest X-Ray in Patients with Suspected Lung Tumors
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概要
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Objective To review diagnostic procedures, therapeutic modalities, and follow-up methods in patients with suspected lung tumors. Methods We retrospectively examined 70 patients who underwent a complete medical checkup because they had been positive for sputum cytology and had presented no chest X-ray findings for the 10-year period between 1994 and 2004. To make a diagnosis, we conducted the first complete medical checkup that included chest X-ray, sputum cytology, chest computed tomography (CT), and bronchoscopy. In the case that no diagnosis could be made, we repeated the chest X-ray and sputum cytology every 3 to 6 months and additionally conducted chest CT and bronchoscopy according to abnormal findings. Results Among 70 patients, there were 36 and 13 who were diagnosed during the first complete medical checkup and follow-up, respectively, 13 who remained undiagnosed, and eight for whom follow-up was discontinued. Among the 49 diagnosed patients, 40, 8, and 1 patient had lung cancer, upper respiratory tract carcinoma (URTC), and esophageal carcinoma (EC), respectively. Among the 40 patients with lung cancer, 34 had a stage 0 or I tumor and 15 were radically treatable by photodynamic therapy and endobronchial irradiation. Nine among 11 patients whose lung cancer was detected during follow-up had a stage 0 or IA tumor. Conclusion Not only lung cancer but also URTC and EC were successfully detected in patients who were positive for sputum cytology and presented negative chest X-ray. Radical treatment was possible in 38 (76%) of 50 diagnosed patients, thus indicating the importance of follow-up through these procedures.
- 社団法人 日本内科学会の論文
著者
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Takeda Koji
Department Of Cardiovascular Surgery Osaka University Graduate School Of Medicine
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Takifuji Nobuhide
Department of Internal Medicine, Osaka Prefectural Habikino Hospital
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Yamamoto Ryoji
Department Of Environmental Biochemistry Kyoto Pharmaceutical University
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Tada Hirohito
Department Of General Thoracic Surgery Osaka City General Hospital
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Kiyota Hidemi
Department Of Medical Oncology Kinki University School Of Medicine
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Tada Hirohito
Department of Thoracic Surgery, Osaka City General Hospital
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Sumitani Mitsuhiro
Department of Respiratory Medicine, Osaka City General Hospital
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Nanjyo Shigeki
Department of Respiratory Medicine, Osaka City General Hospital
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Imahashi Yumiko
Department of Respiratory Medicine, Osaka City General Hospital
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Kiyota Hidemi
Department of Clinical Oncology, Osaka City General Hospital
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