Immunosuppressive Treatment for Mixed Connective Tissue Disease May Facilitate the Development of Adult T Cell Leukemia/Lymphoma in a HTLVI Carrier

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概要

• 論文の詳細を見る

• A 66yearold woman who was positive for human Tlymphotropic virus type I (HTLVI) antibody developed mixed connective tissue disease (MCTD) with interstitial pneumonia, and was successfully treated with corticosteroid. One year later, under maintenance treatment of prednisolone (PSL), she contracted acute type adult Tcell leukemia/lymphoma (ATLL) without flaring of MCTD. MCTD is considered to be as one of the HTLVIrelated inflammatory diseases, however the development of ATLL during the treatment of HTLVIrelated MCTD has not been well studied. Here, we review the literature and raise the issue of the mutual interactions between MCTDcausative antiHTLVI immune response and antiATLL immune response.

• 社団法人 日本内科学会の論文

著者

• MATSUSHITA Kakushi

  Division of Hematology and Immunology, Internal Medicine, Kagoshima University Hospital

• OZAKI Atsuo

  Division of Hematology and Immunology, Internal Medicine, Kagoshima University Hospital

• HAMADA Heiichiro

  Division of Hematology and Immunology, Internal Medicine, Kagoshima University Hospital

• Tei Chuwa

  Department Of Cardiology Kagoshima University

• Nakamura Daisuke

  Division of Cardiology, Osaka Rosai Hospital

• Fujiwara Hiroshi

  Division Of Cardiology Hemotology And Endocrinology Niigata University Graduate School Of Medical An

• Matsumoto Tadashi

  Division Of Hematology Jiaikai Imamura Hospital

• Tei Chuwa

  Department of Cardiovascular, Respiratory and Metabolic Medicine, Graduate School, Kagoshima University, Kagoshima

• Nakamura Daisuke

  Division of Hematology and Oncology, Jiaikai Imamura Hospital, Kagoshima

• Kukita Toshimasa

  Division of Hematology and Oncology, Jiaikai Imamura Hospital, Kagoshima

• Ozaki Atsuo

  Division of Hematology and Immunology, Department of Internal Medicine, Kagoshima University, Kagoshima

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