Late-onset Life Threatening Hemorrhage of Omeprazole-Resistant Duodenal Ulcer Managed by Interventional Radiology: Report of a Case
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概要
- 論文の詳細を見る
A 67-year-old diabetic man was emergently hospitalized in our department because of a huge duodenal ulcer without visible vessels. Despite of intravenous administration of 40 mg omeprazole and fasting with intravenous nutritional support, endoscopically unmanageable massive bleeding occurred on the 8th hospital day. Emergent angiography showed extravasation of contrast media from a duodenal branch of the proper hepatic artery, and superselective arterial embolization was successfully achieved. The patient recovered from the hemorrhagic shock and underwent subsequent successful surgery. Analysis of CYP2C19 enzyme genotype indicated the patient was a homozygous extensive metabolizer, considered a poor responder for omeprazole treatment.
- 社団法人 日本内科学会の論文
著者
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Kitamura Masayuki
Department Of Radiology National Center For Child Health And Development
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Iida Mitsuo
Department Of Medical And Clinical Science Graduate School Of Medical Sciences Kyushu University
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Nakamori Mari
Department Of Anatomic Pathology Graduate School Of Medical Sciences Kyushu University
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Hizawa Kazuoki
Department Of Internal Medicine Kyushu Central Hospital
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Hasegawa Hirofumi
Department Of Surgery And Science Graduate School Of Medical Sciences Kyushu University
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Matsumoto Takayuki
Department Of Electronics Information And Communication Engineering Waseda University
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Miura Nobutoshi
Department of Radiology, Kyushu Central Hospital
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