Emerging Minimal-change Nephrotic Syndrome in a Patient with Chronic Mesangial Proliferative Lupus Nephritis

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概要

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• A 41-year-old Japanese woman with a 25-year history of systemic lupus erythematosus was admitted because of abrupt onset of nephrotic syndrome and acute renal failure. Renal biopsy specimen showed only mild mesangial proliferative glomerulonephritis associated with mesangial deposition of immunoglobulins/complements. No significant immune deposits were found in the glomerular capillary walls, but mild foot process effacement was observed on electron microscopy. Further, two-month corticosteroid therapy improved her massive proteinuria and renal dysfunction, indicating that this patient showed minimal-change nephropathy superimposed on mesangial proliferative lupus nephritis.

• 社団法人 日本内科学会の論文

著者

• Uzu Takashi

  Department Of Medicine Shiga University Of Medical Science

• Sugimoto Toshiro

  Department Of Internal Medicine Shiga University Of Medical Science

• Sakaguchi Masayoshi

  Department Of Applied Biological Science Tokyo University Of Agriculture And Technology

• Tanaka Yuki

  Department Of Applid Science For Electronics And Materials Graduate School Of Engineering Sciences K

• Nishio Yoshihiko

  Department Of Diabetes And Endocrine Medicine Kagoshima University Graduate School Of Medical And Dental Science

• Kashiwagi Atsunori

  Department of Internal Medicine, Shiga University of Medical Science

• Deji Naoko

  Department of Internal Medicine, Shiga University of Medical Science

• Aoyama Masahiro

  Department of Internal Medicine, Shiga University of Medical Science

• Kanasaki Masami

  Department of Internal Medicine, Shiga University of Medical Science

• Uzu Takashi

  Department of Internal Medicine, Shiga University of Medical Science

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