Mean Arterial Pressure: A Better Marker of Stroke in Patients with Uncontrolled Hypertension in Rural Areas of China
スポンサーリンク
概要
- 論文の詳細を見る
Objective The purpose of this study was to compare the association of pulse pressure (PP) and mean arterial pressure (MAP) with stroke in uncontrolled hypertensive subjects. Methods A total of 9,901 uncontrolled hypertensive subjects were included in a cross-sectional study in 62 villages of Fuxin county of Liaoning Province, China. Results Among the 9,901, 406 cases of ischemic stroke and 145 cases of cerebral hemorrhage were identified. Older age, male gender, increased SBP, higher DBP, and history of hyperlipemia were positively associated with both ischemic stroke and cerebral hemorrhage by multivariate logistic regression analysis. However, the odds rations (ORs) of drinking for ischemic stroke and cerebral hemorrhage were 0.407 (95%CI: 0.304-0.544) and 0.595 (95%CI: 0.377-0.940), respectively. An increase of 10 mmHg of MAP had ORs of 1.430 (95%CI: 1.332-1.535) for ischemic stroke and 1.359 (95%CI: 1.220-1.514) for cerebral hemorrhage. The OR of PP (per 10 mmHg increase) for ischemic stroke was 1.085 (95%CI: 1.026-1.148). Subjects with the fourth quartile of PP and MAP had ORs of 1.555 (95%CI: 1.127-2.146) ischemic stroke and 5.127 (95%CI: 3.452-7.616) for cerebral hemorrhage, with the first quartile as the reference group. The OR of the fourth quartile of MAP for cerebral hemorrhage was 5.935 (95%CI: 2.932-12.012). There was no significant association between PP and cerebral hemorrhage. In sensitivity analysis, ORs of standard MAP for ischemic stroke were higher than those of PP in each stratified age subgroup. Conclusions Increased MAP and PP were significant markers of ischemic stroke and cerebral hemorrhage was only associated with increased MAP. MAP was more closely associated with stroke than PP in patients with uncontrolled hypertension.
- 社団法人 日本内科学会の論文
著者
-
Hu Dayi
Heart Center People's Hospital Of Peking University People's Republic Of China
-
Wei Yidong
Heart Lung And Blood Vessel Center Tongji University
-
Li Jue
Heart Lung And Blood Vessel Center Of Tongji University
-
Yu Jinming
Heart Lung And Blood Vessel Center Tongji University
-
Sun Yingxian
Department Of Cardiology The Second Affiliated Of China Medical University
-
Hu Dayi
Heart, Lung and Blood Vessel Center, Tongji University
-
Yu Jinming
Heart, Lung and Blood Vessel Center, Tongji University
-
Zheng Liqiang
Department of Cardiology, The Second Affiliated Hospital of China Medical University
-
Sun Zhaoqing
Department of Cardiology, Shengjing Hospital of China Medical University, People's Republic of China
-
Sun Zhaoqing
Department of Cardiology, The Second Affiliated Hospital of China Medical University
-
Zhang Xingang
Department of Cardiology, The Second Affiliated Hospital of China Medical University
-
Liu Shuangshuang
Department of Cardiology, The Second Affiliated Hospital of China Medical University
-
Li Jiajin
Department of Cardiology, The Second Affiliated Hospital of China Medical University
-
Xu Changlu
Department of Cardiology, The Second Affiliated Hospital of China Medical University
-
Zhang Xingang
Department of Cardiology, the First Affiliated Hospital of China Medical University, People's Republic of China
-
Li Jue
Heart, Lung and Blood Vessel Center, Tongji University
-
Sun Yingxian
Department of Cardiology, The Second Affiliated Hospital of China Medical University
関連論文
- Study on the Relationship of APACHE III and Levels of Cytokines in Patients with Systemic Inflammatory Response Syndrome after Coronary Artery Bypass Grafting(Biochemistry)
- Prevalence of Peripheral Arterial Disease and Risk Factors for the Low and High Ankle-Brachial Index in Chinese Patients with Type 2 Diabetes
- PE-440 Prevalence of Peripheral Arterial Disease and Risk Factors for Ankle-brachial Index in Chinese Patients with Type 2 Diabetes(Diabetes/Obesity/Metabolic syndrome-5 (H) PE74,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of t
- PE-281 Ankle Brachial Index as Atherosclerosis Marker in Chinese High Cardiovascular Risk Patients(Peripheral circulation-5 (H) PE47,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- The Characteristics of Living and Behavioral Factors in Chinese Patients with Metabolic Syndrome
- OE-264 Ankle-brachial index as a predictor of All-Cause and Cardiovascular Disease Mortality in Chinese Patients with High Cardiovascular Risk(Peripheral circulation/Vascular disease(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of
- Evaluation of Medical Treatment for Peripheral Arterial Disease in Chinese High-Risk Patients
- Prevalence and Risk Factors of the Rural Adult People Prehypertension Status in Liaoning Province of China
- PE-516 Investigation on Correlative Risk Factors and Epidemic Characteriazation of Hypertension among Rural Adult Groups in Liaonong Province(Hypertension, clinical-07, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-515 Prevalence and Risk Factors of the Rural Adult People Prehypertension Status in Liaoning Province of China(Hypertension, clinical-07, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-600 The Relationship between Blood Glucose Metabolism and Cardiac or Cerebral Vascular Diseases of Identified Metabolic Syndrome in Chinese Patients(Metabolism/Biochemistry/Energetics-2 (M) PE105,Poster Session (English),The 70th Anniversary Annual Sci
- PE-117 The Preventive Effect of Fastigial Nucleus Stimulation on the Oxidative Damage from Myocardial Infarction in Rats(Acute myocardial infarction, basic-3 (IHD) PE20,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanes
- Investigation of Blood Lipid Levels and Statin Interventions in Outpatients With Coronary Heart Disease in China : The China Cholesterol Education Program (CCEP)
- The Predictive Value of Brachial-Ankle Pulse Wave Velocity in Coronary Atherosclerosis and Peripheral Artery Diseases in Urban Chinese Patients
- Sensitivity and Specificity of Ankle-Brachial Index for Detecting Angiographic Stenosis of Peripheral Arteries
- Prevalence, Awareness, Treatment, and Control of Hypertension in Rural Adults from Liaoning Province, Northeast China
- PE-514 Pulse Pressure and Mean Arterial Pressure to Identify Individuals with Stroke among Uncontrolled Hypertensive Subjects of Chinese Rural Areas(Hypertension, clinical-07, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-595 Prevalence of Coronary Heart Disease in Hemodialysis Patients with Chronic Renal Failure : A Multi-center Clinical Study(Kidney/Renal circulation-3 (H) PE104,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Ci
- PE-587 The Relationship between Lipoprotein Lipase Ser447Ter Gene Variants and Hypertension of Chinese Patients(Hypertension, clinical-7 (H) PE102,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- PE-418 Evaluation of Lower Extremity Peripheral Arterial Disease in Hemodialysis Patients with Chronic Renal Failure by Measuring the Ankle-brachial Index(Kidney/Renal circulation-2 (H) PE70,Poster Session (English),The 70th Anniversary Annual Scientific
- PE-344 The Specificity of Ankle-brachial Index to Assess Peripheral Arterial Disease in High Risk Patients with Metabolic Syndrome(Diabetes/Obesity/Metabolic syndrome-6 (H) PE58,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of th
- PE-280 Prevalence of Peripheral Arterial Disease in High-risk Chinese Patients : A Multi-Center Clinical Study(Peripheral circulation-5 (H) PE47,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- PE-279 Evaluation of Lower Extremity Peripheral Arterial Disease in Hospitalized Patients with Ischaemic Stroke by Measuring the Ankle-brachial Index(Peripheral circulation-5 (H) PE47,Poster Session (English),The 70th Anniversary Annual Scientific Meeting
- PE-262 A Study on the Interaction Lipoprotein Lipase Ser447Ter Gene Variants with Ischemic Stroke Patients(Lipid disorders-2 (H) PE44,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Rem Protein Expression Effects the Ca Channel Function of Embryonic Ventricular Myocytes(Excitation-contraction Coupling/Ion Channel 1 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- T-type Calcium Channels (CaV3.1) Contribute to Spontaneous Activity of Embryonic Ventricular Myocytes(Excitation-contraction Coupling/Ion Channel 1 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- The Association between Ankle-Brachial Index and Cardiovascular or All-Cause Mortality in Metabolic Syndrome of Elderly Chinese
- Effect of Statins and Calcium Channel Blockers on All-Cause Mortality and Cardiovascular and Cerebrovascular Disease Mortality in 958 Chinese Hospitalized Patients with Peripheral Arterial Disease after 13 Months of Follow-up
- Risk Factors of Peripheral Arterial Disease and Relationship Between Low Ankle-Brachial Index and Mortality From All-Cause and Cardiovascular Disease in Chinese Patients With Type 2 Diabetes
- PE-351 Prevalence of Dyslipidemia and Associated Factors Among the Hypertensive Rural Chinese Population(Lipid disorders(03)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PE-068 The prevalence of metabolic syndrome among the hypertensive rural adults in China(Diabetes/Obesity/Metabolic syndrome(04)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Differential Control of Systolic and Diastolic Blood Pressure : Factors Associated With Lack of Blood Pressure Control in Rural Community of Liaoning Province, China
- Lower Extremity Peripheral Arterial Disease in Hospitalized Patients with Coronary Disease(Peripheral Circulation/Vascular Disease 5 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Study on the Risk Factors of Postoperative Hypoxemia in Patients Undergoing Coronary Artery Bypass Grafting
- An Epidemiological Study on the Prevalence of Atrial Fibrillation in the Chinese Population of Mainland China
- PE-138 Effects of Fastigial Nucleus Stimulation on Heart Rate Variability in Myocardial Infarction Rats(Autonomic nervous system-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Ankle Brachial Index as a Marker of Atherosclerosis in Chinese Patients with High Cardiovascular Risk
- Prehypertension in Children and Adolescents: Association with Body Weight and Neck Circumference
- Mean Arterial Pressure: A Better Marker of Stroke in Patients with Uncontrolled Hypertension in Rural Areas of China
- Body Mass Index and the Prevalence of Prehypertension and Hypertension in a Chinese Rural Population