Coronary Arterial Plaque Characterized by Multislice Computed Tomography Predicts Complications Following Coronary Intervention

スポンサーリンク

概要

• 論文の詳細を見る

• Background: A reliable, noninvasive assessment of plaque configuration would constitute an important step forward for predicting complications following percutaneous coronary intervention (PCI). Multislice computed tomography (MSCT) holds promise with respect to allowing for differentiation of coronary lesion configuration. However, it has not yet been clarified whether the characteristics of coronary artery plaque measured by MSCT predict complications after PCI. The aim of this study was to investigate the relationship between plaque configuration and complications after coronary intervention in patients with stable angina pectoris. Methods: MSCT was performed in patients with angina pectoris who were scheduled for PCI prospectively, and 26 patients (70 ± 11 years, 18 males) with coronary artery plaque in a stenotic coronary artery measured by MSCT were recruited for this study. Thirty-five plaques in the stenotic coronary lesions were divided into 3 groups based on the CT density as soft, intermediate, and hard, and were compared with the complications after PCI. Results: The soft plaque group before PCI (n = 11) was significantly associated with the appearance of slow flow (n = 4) or a compromised side branch (n = 1) after PCI, whereas the hard plaque group before PCI (n = 17) was associated with the appearance of dissection (n = 2) or perforation (n = 1) after PCI (P = 0.004). The intermediate plaque group (n = 7) had only one complication, a compromised side branch (n = 1). Conclusion: Coronary arterial plaque characterized by MSCT can predict intervention-related complication. It may be important for the risk stratification of the patients scheduled to undergo PCI to investigate plaque configuration by MSCT.

• International Heart Journal刊行会の論文

著者

• Akutsu Yasushi

  Third Department of Internal Medicine, Showa University School of Medicine

• Li Hui-Ling

  Third Department of Internal Medicine, Showa University School of Medicine

• Kinohira Yukihiko

  Third Department Of Internal Medicine Showa University

• Gokan Takehiko

  Department Of Radiology School Of Medicine Showa University

• Yamanaka Hideyuki

  Third Department Of Internal Medicine

• Nishimura Hideki

  Third Department Of Internal Medicine Showa University School Of Medicine

• Katagiri Takashi

  Third Department Inter Nat Medicine Showa University

• Sakurai Masayuki

  Third Department of Internal Medicine (Division of Cardiology), Showa University School of Medicine

• Shinozuka Akira

  Division of Nuclear Medicine, Showa University School of Medicine

• Kodama Yusuke

  Third Department of Internal Medicine (Division of Cardiology), Showa University School of Medicine

• Hamazaki Yuji

  Third Department of Internal Medicine (Division of Cardiology), Showa University School of Medicine

• Saiki Yuka

  Third Department of Internal Medicine (Division of Cardiology), Showa University School of Medicine

• Akutsu Yasushi

  Third Department of Internal Medicine (Division of Cardiology), Showa University School of Medicine

• Li Hui-Ling

  Third Department of Internal Medicine (Division of Cardiology), Showa University School of Medicine

関連論文

• 梗塞責任冠動脈への再血行再建術を予測する危険因子に関する検討
• 8) 運動負荷試験時冠攣縮が誘発された冠攣縮性狭心症の一例
• 23)門脈圧亢進症を伴う著明な肺高血圧症の一例(第200回日本循環器学会関東甲信越地方会)
• シベンゾリンと右室ペーシングにより著明な左室内圧較差の改善を認めた高齢者閉塞性肥大型心筋症の1例(第196回日本循環器学会関東甲信越地方会)
• 右冠動脈入口部病変に対するシロリムス溶出ステントの治療成績の検討
• 41) 急性心筋梗塞後に発症したElectrical Stormに対しカテーテルアブレーションで救命した1例(第208回日本循環器学会関東甲信越地方会)
• RELATIONSHIP BETWEEN ENERGY METABOLISM AND CONTRACTILE RECOVERY IN STUNNED MYOCARDIUM
• 急性心筋梗塞発症時非責任冠動脈にプラーク破綻し血栓性の有意狭窄を生じたが冠動脈造影上, 同部位の血栓の消失を認めた1例
• 透析症例におけるシロリムス溶出性ステントの臨床成績 : 非透析症例との比較検討
• タコつぼ型心筋症の4症例 (報告集 第22回東京CCU研究会) -- (一般演題 医師部門)
• 53)三尖弁輪側壁に起源をゆうしたATP感受性心房頻拍の一例
• PJ-411 Clinical and Angiographic Results after Sirolimus-eluting Stents Implantation Using Several Stenting Techniques for Left Main Bifurcation Lesion(PJ069,Coronary Revascularization, PCI (Restenosis/Others) 1 (IHD),Poster Session (Japanese),The 73rd An
• PJ-406 Impact of Coronary Hinge Motion Caused Restenosis after Silolimus-Eluting Stent Implantation, Treatment Strategy for the Restenosis(PJ069,Coronary Revascularization, PCI (Restenosis/Others) 1 (IHD),Poster Session (Japanese),The 73rd Annual Scientif
• High-Dose Granulocyte-Colony Stimulating Factor Promotes Neointimal Hyperplasia in the Early Phase and Inhibits Neointimal Hyperplasia in the Late Phase After Vascular Injury
• PJ-901 Strong Correlation between Small LDL-Cholesterol and Negative Net Charge Fraction of LDL in Patients with and without Coronary Artery Disease(Lipid disorders(05)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circula
• PJ-818 Riskfactor of restenosis after percutaneous coronary intervention with Sirolimus-eluting stent(Coronary revascularization, PCI(26)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-233 Elevated Small Dense Low-density Lipoprotein Cholesterol to Risk Marker for Stable Coronary Heart Disease, Independent of Adiponectin and C-reactive protein(Atherosclerosis,clinical(10)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeti
• PJ-167 Remarkably High Levels of Small LDL-cholesterol in Younger Patients with Acute Coronary Syndrome and Metabolic Syndrome(Preventive medicine/Epidemiology/Education(05)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Ci
• PE-502 Not LDL-Cholesterol But Apolipoprotein A1 is an Important Risk Marker for Severe Coronary Atherosclerosis in Patients Treated with Lipid-lowering Drugs(Atherosclerosis, clinical(08)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of
• 2 High Levels of Small Dense LDL-cholesterol as Atherogenic and Metabolic LDL in Patients with Acute Coronary Syndrome(Symposium 3 (SY-03) (IHD) Metabolic Syndrome and Atherosclerosis,Special Program,The 72nd Annual Scientific Meeting of the Japanese Circ
• PJ-811 Effect of Candesartan on the Lipid Metabolism of Hypertensive Patients with Focused on Small Dense LDL-C(Hypertension, clinical-10, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-809 ACE-Inhibitors and Angiotensin II Receptor Antagonists (ARB) Have Stronger Effects on Matrix Metalloproteinase Pathway and Anti-inflammation than Ca-antagonists(Hypertension, clinical-10, The 71st Annual Scientific Meeting of the Japanese Circulati
• PJ-285 Histological Features Around the Three Aortic Cusp Regions, Implication for the Radiofrequency Catheter Ablation for Atrial and Ventricular Tachycardia(Arrhythmia, diagnosis/pathophysiology/EPS-14, The 71st Annual Scientific Meeting of the Japanese
• PJ-901 Strong Correlation between Small LDL-Cholesterol and Negative Net Charge Fraction of LDL in Patients with and without Coronary Artery Disease(Lipid disorders(05)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circula
• PJ-233 Elevated Small Dense Low-density Lipoprotein Cholesterol to Risk Marker for Stable Coronary Heart Disease, Independent of Adiponectin and C-reactive protein(Atherosclerosis,clinical(10)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeti
• PJ-167 Remarkably High Levels of Small LDL-cholesterol in Younger Patients with Acute Coronary Syndrome and Metabolic Syndrome(Preventive medicine/Epidemiology/Education(05)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Ci
• PE-502 Not LDL-Cholesterol But Apolipoprotein A1 is an Important Risk Marker for Severe Coronary Atherosclerosis in Patients Treated with Lipid-lowering Drugs(Atherosclerosis, clinical(08)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of
• 2 High Levels of Small Dense LDL-cholesterol as Atherogenic and Metabolic LDL in Patients with Acute Coronary Syndrome(Symposium 3 (SY-03) (IHD) Metabolic Syndrome and Atherosclerosis,Special Program,The 72nd Annual Scientific Meeting of the Japanese Circ
• PJ-809 ACE-Inhibitors and Angiotensin II Receptor Antagonists (ARB) Have Stronger Effects on Matrix Metalloproteinase Pathway and Anti-inflammation than Ca-antagonists(Hypertension, clinical-10, The 71st Annual Scientific Meeting of the Japanese Circulati
• PJ-285 Histological Features Around the Three Aortic Cusp Regions, Implication for the Radiofrequency Catheter Ablation for Atrial and Ventricular Tachycardia(Arrhythmia, diagnosis/pathophysiology/EPS-14, The 71st Annual Scientific Meeting of the Japanese
• Effects of Physical Training on the Recovery of the Autonomic Nervous Activity During Exercise After Coronary Artery Bypass Grafting : Effects of Physical Training After CABG
• 1010 EFFECTS OF TRAINING ON AUTONOMIC NERVE ACTIVITY AFTER CORONARY ARTERY BYPASS SURGERY
• 105)寛解期にも高度の活動性心筋障害が持続した心不全を繰り返す心アミロイドーシスの一例(日本循環器学会 第181回関東甲信越地方会)
• PJ-143 Synergistic Effects of Cardiac Rehabilitation with Lipid-lowering Therapy on Amelioration of Small Dense LDL in Patients with Acute Coronary Syndrome(Acute coronary syndrome, basic/clinical-7, The 71st Annual Scientific Meeting of the Japanese Circ
• PJ-073 Mechanism of Neurally Mediated Syncope(Autonomic nervous system-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-455 Increases in Serum Metalloproteinase-1, -13, and Interleukin-6 in the Culprit Coronary Artery in Patients with Acute Myocardial Infarction(Infection/Inflammation/Immunity-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-301 Low-density Lipoprotein (LDL)-cholesterol Levels Under Estimate Atherogenic LDL-cholesterol at Onset Acute Coronary Syndrome(Atherosclerosis, clinical-07, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-291 Significance of Small Dense LDL-Cholesterol, CRP, and Adiponectin as a Biomarkers to Predict Coronary Events in Stable Coronary Heart Disease(Atherosclerosis, clinical-06, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-169 Effect of Frequent Cardiac Rehabilitation on Heart Rate Recovery after Exercise(Exercise test/Cardiac rehabilitation-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-262 Effects of Pioglitazone on the Metabolic Syndrome Complicated with Hypertension plus Diabetes Mellitus(Cardiovascular pharmacology, basic/clinical-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-582 Effects of the Frequency of Exercise-Based Cardiac Rehabilitation on Glucose Tolerance or Intolerance in Patients with Acute Coronary Syndrome(Exercise test/Cardiac rehabilitation-2 (IHD) PE101,Poster Session (English),The 70th Anniversary Annual S
• Effects of the Frequency of Exercise-Based Cardiac Rehabilitation after Acute Coronary Syndrome on Atherogenic Dyslipidemia(Exercise Training and Cardiac Rehabilitation (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• The Involvement of TNF-α on Myocardial Remodeling after AMI through MMP Expression
• Matrix Metalloproteinases Are Involved in Pathogenesis of In-Stent Restenosis in Porcine
• The Expression of Stem Cell Marker in Neointima of In-Stent Resteonsis in Porcine Coronary Arteries
• Local delivery of a specific Rho-kinase inhibitor suppressed vascular remodeling after balloon angioplasty In porcine coronary arteries
• The Expression of Intercellular Adhesion Molecule-1 and Vascular Cell Adhesion Molecule-1 in Pig Coronary Arteries following Coronary Intervention
• Biochemical and Ultrastructural Evaluations of the Effect of Ischemic Preconditioning on Ischemic Myocardial Injury : Role of the Adenosine Triphosphate-Sensitive Potassium Channel
• Histochemical studies of myocardial injury caused by hydrogen peroxide after reperfusion using the cerium method
• P767 CHANGING PATTERN OF DELTA WAVE BY EXERCISE LOAD IN WOLFF-PARKINSON-WHITE SYNDROME
• P636 ROLE OF ANGIOTENSIN II RECEPTOR ON VENTRICULAR REMODELING AFTER MYOCARDIAL INFARCTION
• OE-221 A Combination of Sympathetic Nervous System Abnormality and Left Ventricular Dysfunction for Predicting Recurrent Ventricular Tachyarrhythmic Events(OE38,Nuclear Cardiology (Others) (I),Oral Presentation (English),The 73rd Annual Scientific Meeting
• OJ-174 Cardiac Sympathetic Nerve Abnormality predicts Sudden Cardiac Deathin Patients with Ventricular Tachyarrhythmias(Nuclear cardiology(02)(I),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-674 Efficacy of Cypher Stent in the Treatment for RCA Ostial Lesion(Coronary revascularization, PCI-22 (IHD) PJ113,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• OE-003 Regional Expression of Tissue Factor in Thrombus in Acute Coronary Syndrome : Immunohistochemical Analysis for Aspiration Samples(Acute coronary syndrome, basic/clinical-1 (IHD) OE1,Oral Presentation (English),The 70th Anniversary Annual Scientific
• Significance of I-123 Metaiodobenzylguanidine Scintigraphic Imaging as Screening of the Arrhythmogenic Disorder in Outpatients with Palpitation (Nuclear Cardiology 13 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Comparative Examination Between Right And Left Coronary Thrombus in Acute Coronary Syndrome : Histological and Immunohistochemical Analysis(Acute Coronary Syndrome/Changing Strategy (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Soc
• PE-040 Difference in cause of congestive heart failure between the patients with chronic and paroxysmal atrial fibrillation.(Nuclear Cardiology 5 (I) : PE7)(Poster Session (English))
• PE-038 Mismatch among Function, Perfusion and Metabolism For Predicting Final Functional Recovery in Adyskinetic Infarct-related Myocardium 1 month after Angioplasty(Nuclear Cardiology 5 (I) : PE7)(Poster Session (English))
• OJ-316 Change with exercise in QT dispersion for detecting the condition of infarct-related myocardium including myocardial scar after angioplasty(Nuclear Cardiology 7 (I) : OJ38)(Oral Presentation (Japanese))
• OE-029 Changes in Cytokines and MMPs Levels in Aspirated Serum in Acute Myocardial Infarction(Acute Myocardial Infarction, Clinical (Pathophysiology) 1 (IHD) : OE4)(Oral Presentation (English))
• FRS-103 Eosinophils may have potential to promote occlusive thrombus in acute coronary syndrome : histological and immunohistochemical analysis(Acute Coronary Syndrome (IHD) : FRS13)(Featured Research Session (English))
• Difference in Ischemic Burden during and after Exercise between Exercise-Induced Painful Ischemia and Painless Ischemia Distinguishing Diabetes Mellitus
• The Effect of Candesartan on the Left Ventricular Remodeling after Acute Myocardial Infarction
• Recovery Sequence within Ischemic Territory after Exercise-Induced Ischemia : A Study Using Dual-Isotope Perfusion Single Photon Emission Tomography
• OJ-032 Measurement of the Left Atrial Isthmus and Obstacles(Arrhythmia, therapy-05, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• FRS-003 Impact of Circulating Tissue Factor and Prasminogen Activator Inhibitor-1 on Thrombus Proliferation in Acute Coronary Syndrome : Immunohistochemical Analysis(Acute Coronary Syndrome, The 71st Annual Scientific Meeting of the Japanese Circulation S
• The Effects of Nicorandil and Nifekalant, Which Were Injected into the Pericardial Space, for Transmural Dispersion of Repolarization in the Pig
• Arrangement of the Autonomic Nerves Around the Pulmonary Vein-Left Atrial Junctions : Histologic and Immunohistochemical Analyses
• Epicardial Ablation With Cooled Tip Catheter Close to the Coronary Arteries is Effective and Safe in the Porcine Heart if the Ventricular Potential is Being Monitored in the Epicardium and Endocardium
• PJ-620 Treating to Atrial Fibrillation with Pulmonary Vein Isolation(Arrhythmia, therapy-18 (A) PJ104,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-448 Diverse Myocardial Extension and Autonomic Innervation on Ligament of Marshall in Humans(Arrhythmia, diagnosis/pathophysiology/EPS-11 (A) PJ76,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Soci
• PE-039 The Role of ICD in Sudden Cardiac Death for Japanese Patient(Arrhythmia, therapy-8 (A) PE7,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-209 Histological Observation of the Radiofrequency Ablative Lesions for Scar-Related Ventricular Tachycardia Guided by Electroanatomical Mapping System(Arrhythmia, therapy-4 (A) OJ35,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific M
• Restoration of Sinus Rhythm from Ventricular Fibrillation in Patients with Sudden Cardiac Death (Arrhythmia, Non-pharmacological Therapy 9 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• The Distribution of the Autonomic Nerves Contiguous with the Entrance of the Pulmonary Veins in Humans(Arrhythmia, Diagnosis/Pathophysiology/EPS 4 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Human Urotensin-II Potentiates the Mitogenic Effect of Mildly Oxidized Low-Density Lipoprotein on Vascular Smooth Muscle Cells : Comparison with Other Vasoactive Agents and Hydrogen Peroxide
• A Single Nucleotide Polymorphism in the Carboxylesterase Gene Is Associated with the Responsiveness to Imidapril Medication and the Promoter Activity
• Small Dense LDL and Carotid Atherosclerosis in Relation to Vascular Dementia
• Ultrastructural and biochemical studies of ischemic preconditioning using an adenosine receptor blocker and an ATP-sensitive K channel opener
• OE-307 Small Dense Low-Density Lipoprotein (LDL)-Cholesterol is a more Powerful Marker than LDL-Cholesterol in Determining Severe Coronary Atherosclerosis(Atherosclerosis, clinical-02, The 71st Annual Scientific Meeting of the Japanese Circulation Society
• Carperitide Exerts Its Therapeutic Effects through IL-6 Inhibition in Acutely Decompensated Heart Failure
• PE-164 Significance of Small Dense Low-density Lipoprotein-Cholesterol Concentrations in Relation to the Severity of Coronary Heart Diseases(Atherosclerosis, clinical-7 (H) PE28,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of th
• Significance of Overlap of Tc-Pyrophosphate/TL-201 in Acute Infarct-Related Myocardium in Patients Underwent Complete Recanalization (TIMI Grade 3)
• Significance of ST-Segment Depression During Adenosine Triphosphate Stress 201-Thallium Scintigraphy in Coronary Artery Disease
• Hypertrophic Cardiomyopathy With Apical Left Ventricular Aneurysm
• Thin-wall Cystic Tumors in the Retroperitoneum : CT and MRI
• Correlations Between Resting Regional Wall Motion and Regional Myocardial Blood Flow (at Rest and During Exercise) in Infarct-Related Myocardium : A Study With [^N]Ammonia Positron Emission Tomography
• DETERMINATION OF REGIONAL MYOCARDIAL BLOOD FLOW WITH ^N-AMMONIA POSITRON EMISSION TOMOGRAPHY DURING LOW-GRADE EXERCISE FOR EVALUATING CORONARY ARTERY STENOSIS
• Association between Smoking Behavior and Small Dense Low-Density Lipoproteins in Patients with Coronary Heart Disease
• Rental Cyst Pseudoenhancement with Beam Hardening Effect on CT Attenuation
• PJ-374 Evaluation of Left Ventricular Function Using ECG-gated 16-slice MDCT : in Comparison to SPECT with Tc-tetrofosmin(CT/DSA-6 (I) PJ63,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• Multi-volume Fusion Imaging of MR Ductography and MR Mammography for Patients with Nipple Discharge
• Correlation between Myocardial Blood Flow and Fasting Glucose Metabolism in Ischemic Heart Disease : Quantitative Assessment by Nitrogen-13 Ammonia and Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography
• Coronary Arterial Plaque Characterized by Multislice Computed Tomography Predicts Complications Following Coronary Intervention
• Relation between Cardiac Index and Regional Myocardial Blood Flow in the Non-infarcted Wall Using PET with 13NH3 in Healed Myocardial Infarction.
• Significance of Downsloping ST- Segment Depression Induced by Low-level Exercise in Severe Coronary Artery Disease. Assessment with Myocardial Ischemia and Collateral Perfusion.:Assessment with Myocardial Ischemia and Collateral Perfusion
• Usefulness of Simultaneous Evaluations of Contractile Reserve, Perfusion, and Metabolism During Dobutamine Stress for Predicting Wall Motion Reversibility (Myocardial Stunning) After Successful PTCA
• Severity of Exercise-induced Ischemia With Chest Pain and Recovery From Ischemia After the Disappearance of Chest Pain
• Contractile Reserve, Thallium-201 Reverse Redistribution and Mismatch Between Perfusion and Metabolism in Reperfused Infarct-related Myocardium With Delayed and Incomplete Functional Recovery

もっと見る 閉じる

スポンサーリンク