Spontaneous Cerebelar Dysplasias in BrlHan: Wist@Jcl Rats
スポンサーリンク
概要
- 論文の詳細を見る
Focal disturbed laminar architecture in cerebellar vermis was observed in 25 out of 100 (25%) males, and 25 out of 100 (25%) females of BrlHan: WIST@Jcl rats. The cortical molecular and granular layers were haphazardly distributed around the primary and/or secondary fissures. The stellate and basket cells positively stained with parvalbumin immunohistochemistry were observed exclusively in the separated molecular layer. Purkinje cells were found at the boundary between the molecular and the granular layers. Glial fibrillary acid protein (GFAP) immunohistochemistry revealed disarranged fibers of the Bergman glial cells. Based on the incidence of this spontaneous cerebellar lesion, it was presumed to be related to certain genetic factors of this rat strain.
- 社団法人 日本実験動物学会の論文
- 2003-04-01
著者
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ADACHI Tamiko
Drug Safety Research Laboratories, TANABE Seiyaku Co., Ltd.
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YUASA Hirofumi
Safety Research Laboratory
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YUASA Hirofumi
Tanabe
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Kuwamura Y
Tanabe Seiyaku Co. Ltd. Safety Research Laboratory
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Adachi Tamiko
Drug Safety Research Laboratories Tanabe Seiyaku Co. Ltd.
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Yuasa Hirofumi
Tanabe Seiyaku Co. Ltd. Safety Research Laboratory
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Takatani Hiromi
Tanabe Seiyaku Co. Ltd. Safety Research Laboratory
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KUWAMURA Yuki
Tanabe Seiyaku Co., Ltd., Safety Research Laboratory
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ADACHI Tamiko
Tanabe Seiyaku Co., Ltd., Safety Research Laboratory
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