MR imaging of the liver after microwave coagulation therapy for hepatocellular carcinoma

概要

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Intraoperative microwave tissue coagulation (MTC) therapy was applied to 9 hepatocellular carcinoma (HCC) lesions in 5 patients. Magnetic resonance (MR) imaging was used to evaluate changes before and at two and four weeks after treatment. Two weeks after treatment, all coagulated lesions had mildly hyper-intensity with a hypo-intensity rim on T1-WI and mixed signal intensity with a hyper-intensity rim on T2-WI. Enhanced T1-WI displayed an enhanced rim corresponding to hypo-intensity rim on T1-WI (and a hyper-intensity rim on T2-WI). Four weeks after treatment, the MR image characteristics of these coagulated lesions had not changed noticeably compared with those two weeks after treatment. Histologic changes correlated well with changes in MR signal intensity. These findings suggested that MR imaging was useful for evaluation of changes after MTC therapy for HCC.