Microwaveと細胞死―これまで知られていなかった細胞死の型―

概要

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We report a novel form cell death, different from both coagulation necrosis and apoptosis. This cell death takes place after microwave coagulation therapy (MCT). MCT treated tissues preserves their shape, nuclei, and arrangement for more than 3 month.Rat liver was treated with microwave, and sacrificed as long as 2 weeks. We also examined clinical samples of MCT treated metastatic liver cancers. They were examined immuno histochemically and enzyme histochemically, and similar morphological changes took place in both rat and human.This kind of cell death caused by microwave is really unique. Microwave is widely used in the histochemical fields for antigen retrieval and fixation. The characteristics of this cell death resembles fixation. Knowledge of this form of cell death and enzyme histochemistry is essential to determine its effectiveness.
特定非営利活動法人 Microwave Surgery研究会の論文