[原著］一側多発病巣を呈した乳癌の臨床病理学的検討 : 乳房温存術を目指して

概要

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We studied the clinicopathological features of breast cancers with unilateral multiple lesions. From 1987 to 2001, we have experienced 27 breast cancer cases with unilateral multiple lesions out of 380 primary breast cancer cases (7.1%) at Naha City Hospital. Of these 27 cases, 21 cases (77.8%) were classified as intraductal spreading type, 5 cases (18.5%) as multicentric breast cancer and one (3.7%) as intramammary lymph node metastasis. The second lesions were located in the same quadrant in 17 patients, in the contiguous quadrant in 7 and in the opposite quadrant in 2. Two patients underwent extended radical mastectomy, 4 underwent standard radical mastectomy and 12 had modified radical mastectomy. Eight patients were treated with breast conserving surgery followed by post operative radiation therapy. Of the 8 patients, 3 patients were defined as margin al positive, however, none of patients developed distant metastasis or local recurrence in the conserved breast tissue during a follow up for 22 to 94 months. We think that breast conserving surgery can be applied in patients of breast cancer with unilateral multiple lesions.
琉球医学会,Ryukyu Medical Associationの論文