[症例報告]絨毛癌および不全流産の細胞診における問題点の検討

概要

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The results of cytological examinations of two choriocarcinomas and one material of incomplete abortion are discussed about the points of differential diagnosis of these diseases. The specimens for the cytological examinations were obtained by scraping from the cut surfaces of the surgically removed materials. The smears revealed many number of abnormal cells which are distributed as scattered single cell or gathering. The abnormal cells had large and thick cytoplasm and hyperchromatic nuclei which were lobulated or multinucleated and they were diagnosed as atypical trophoblasts. In the background, there were necrotic materials and abundant red blood cells. These findings of the cytological examinations were diagnostic for choriocarcinoma. On the other hand, another smears obtained from the materials of uterine curettages also revealed hyperchromatic cells resembled to those found in choriocarcinoma. Then the patient was suspected a choriocarcinoma at first based on the results of cytological examination. However, the later histological examination of the resected uterus did not show any malignancies and the case was finalmy diagnosed as incomplete abortion. This experience lead us to the conclusion that the establishment of definite diagnosis of choriocarcinoma or abortion is difficult by a cytological examination amone.
琉球大学医学部,Faculty of Medicine, University of the Ryukyusの論文