Inhibitory Effects of 5,6,7-Trihydroxyflavones on Tyrosinase
スポンサーリンク
概要
- 論文の詳細を見る
Baicalein (1), 6-hydroxyapigenin (6), 6-hydroxygalangin (13) and 6-hydroxykaempferol(14), which are naturally occurring flavonoids from a set of 14 hydroxyflavonestested, exhibited high inhibitory effects on tyrosinase with respect to L-DOPA,while each of the 5,6,7-trihydroxyflavones 1, 6, 13 or 14 acted as a cofactor tomonophenolase. Moreover, 6-hydroxykaempferol (14) showed the highest activity andwas a competitive inhibitor of tyrosinase compared to L-DOPA. 5,6,7-Trihydroxyflavones 1, 6, 13 or 14 showed also high antioxidant activities. Hence, weconclude that the 5,6,7-trihydroxy-flavones are useful as good depigmentation agentswith inhibitory effects in addition to their antioxidant properties.
- Molecular Diversity Preservation International (MDPI)の論文
著者
-
齊藤 静夏
北大院薬
-
Gao Hong
Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University
-
Kawabata Jun
北海道大学 大学院農学研究院応用生命科学部門
-
Gao Hong
北海道大学 大学院農学研究院応用生命科学部門
-
Saito Shizuka
Lab. Of Food Biochemistry Div. Of Applied Bioscience Graduate School Of Agriculture Hokkaido Univ.
-
Saito Shizuka
Laboratory Of Food Biochemistry Division Of Applied Bioscience Graduate School Of Agriculture Hokkai
-
Gao Hong
Division Of Applied Bioscience Graduate School Of Agriculture Hokkaido University
-
Kawabata Jun
Division Of Applied Bioscience Graduate School Of Agriculture Hokkaido University
-
Saito Shizuka
Laboratory Of Food Biochemistry Division Of Applied Bioscience Graduate School Of Agriculture Hokkai
関連論文
- P-11 ユズリハ科植物由来の新規アルカロイドcalyciphylline C〜Gの構造と生物活性(ポスター発表の部)
- DPPH (=2,2-diphenyl-1-picrylhydrazyl=2,2-diphenyl-1-(2,4,6-trinitrophenyl)hydrazyl) radical-scavenging reaction of protocatechuic acid esters (=3,4-dihydroxybenzoates) in alcohols : Formation of bis-alcohol adduct
- Chebulagic Acid Is a Potent α-Glucosidase Inhibitor
- カテコール型ポリフェノールのラジカル消去活性増大機構 : キノン体生成以降の反応経路が判明
- Inhibitory Effects of 5,6,7-Trihydroxyflavones on Tyrosinase
- Effects of Alcoholic Solvent on Antiradical Abilities of Protocatechuic Acid and Its Alkyl Esters
- Quinone Hemiacetal Formation from Protocatechuic Acid during the DPPH Radical Scavenging Reaction(Organic Chemistry)
- A Novel Oxidative Dimer from Protocatechuic Esters : Contribution to the Total Radical Scavenging Ability of Protocatechuic Esters
- Chebulagic Acid Is a Potent α-Glucosidase Inhibitor