Chebulagic Acid Is a Potent α-Glucosidase Inhibitor

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概要

• 論文の詳細を見る

• Chebulagic acid, isolated form Terminalia chebula Retz, proved to be a reversible and non-competitive inhibitor of maltase with a Ki value of 6.6 μM. The inhibitory influence of chebulagic acid on the maltase-glucoamylase complex was more potent than on the sucrase-isomaltase complex. The magnitude of α-glucosidase inhibition by chebulagic acid was greatly affected by its origin. These results show a use for chebulagic acid in managing type-2 diabetes.

• 社団法人 日本農芸化学会の論文

著者

• Gao Hong

  Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University

• Huang Yi-Na

  Department of Public Health, Hua Xi Medical Center of Sichuan University

• Gao Bo

  Department of Public Health, Hua Xi Medical Center of Sichuan University

• KAWABATA Jun

  Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University

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