持久的運動トレーニング時におけるビタミンB1、B2代謝の変動

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The present study investigated whether thiamine and riboflavin requirements are increased during exercise. Five healthy males (age (mean ±SEM), 21 ±1 years; height, 178 ±1 cm; weight, 65.8 ±1.8 kg) participated in a metabolic experiment comprising a 10-day exercise period (Ex) preceded by a 6-day non-exercise period (non-Ex). Subjects were fed a diet that satisfied recommended dietary allowances in Japan during the 6-day non-Ex period. Energy intake was increased during Ex by increasing all foods in proportion to energy consumption. During Ex, subjects exercised on a bicycle ergometer at an intensity of 60% maximal oxygen intake for 60 min/day on days 1-5 (1st Ex), then 120 min/day on days 6-10 (2nd Ex). Thiamine pyrophosphate (TPP) effect on transketolase and erythrocyte glutathione reductase activity coefficient (EGRAC) for blood, and daily urinary thiamine and riboflavin excretion were measured as indices of nutritional status. Both TPP effect and EGRAC were unchanged during Ex. Urinary thiamine excretion during 2nd Ex was higher than during 1st Ex, which was in turn higher than during non-Ex. Urinary riboflavin excretion was unchanged throughout Ex, so urinary excretion per energy intake 1,000 kcal was lower during 2nd Ex than during non-Ex. These results suggest that thiamine requirements are unchanged, but riboflavin requirements may be increased during exercise.
関東学院大学人間環境学部人間環境学会の論文