Our 10-year Experience in the Management of Newborn Infants with Multiple Congenital Anomalies

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概要

• 論文の詳細を見る

• Purpose : The incidence of multiple congenital anomalies has increased as a result of advances in prenatal and prenatal treatment. A review of all infants born with more than two congenital anomalies was conducted to identify the clinical feature.Methods : Between January, 1989 and December, 1998, a total of 35 neonates with multiple congenital anomalies were referrred to Yamaguchi University Hospital. The Combination of anomalies, manalies, management and clinical course, prenatal diagnosis and treatment, chromosomal anomalies, outcome, and quality of life these infants were examined retrospectively.Rｅｓｕｌｔｓ : Of these 35 infants, 9(25.7%) had chromosomal abnormalities in the form of trisomy 21 in 8, and trisomy 18 in 1. Prenatal　diagnoses were established in 10 infants (28.6%) and a fetal treatment was preformed in 1. There were four deaths (11.4%) caused by trisomy 18, pulmonary hypoplasia, or cardiac anomalies. Among the survivingpatients, two(6.5%) suffered from mental retardation caused by trisomy 21 or a brain anomaly. A total of 18 children (58.1%) required as mental training, defecation training, or medication review. Conclusion : Approximately one fourth of infants with multiple congenital anomalies had chromosomal abnormalities. Chromosomal abnomalities or cardio-pulmonary anomalies were death causes. More than half of children required long-term forrow-up. We should aim to provide well-plannned management to promote good long-term quality of life of neonates with multiple congenital anomalies.

• Yamaguchi University Graduate School of Medicineの論文

著者

• Zempo Nobuya

  First Department Of Surgery Yamaguchi University School Of Medicine

• Esato K

  Department Of Surgery Yamaguchi University School Of Medicine

• Esato Kensuke

  First Department Of Surgery.yamaguchi University School Of Medicine

• Zempo Nobuya

  Department Of Surgery I Yamaguchi University School Of Medicine

• Zempo Nobuya

  First Department Of Surgery Yamaguchi University School Of Medicine.

• Esato Kensuke

  First Department Of Surgery Yamaguchi University School Of Medicine.

• Kuga Takayuki

  Department Of Surgery And Clinical Science Division Of Pediatric Surgery Yamaguchi University Gradua

• Taniguchi Satoshi

  Department Of Surgery And Clinical Science Division Of Pediatric Surgery Yamaguchi University Gradua

• Zenpo Nobuya

  First Department Of Surgery Yamaguchi University School Of Medicine

• Kuga Takayuki

  Department Of Surgery And Clinical Science Division Of Pediatric Surgery Yamaguchi University Gradua

• Inoue Takashi

  Department Of Surgery And Clinical Science Division Of Pediatric Surgery Yamaguchi University Gradua

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