A Case with Neutrophil Infiltration into Nevus Cell Nest after Intravenous Administration of Interferon-β
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概要
- 論文の詳細を見る
Interferon－β therapy has been widely applied for patients with hapatitis C and with malignant melanoma. Its anti-tumor effects on malignant melanoma are well discussed but few reports on anti-tumor effect of the interferon-β to benign tumors are described. A 63-year-old female received interferon-β therapy(dose=6×10 6 units/day) for hepatitis C and developed erythematous change and pain on her intradermal nevus seen on the right external canthus. Histopathological study revealed that the neutrophilic infiltration was localized only in nevus cell nest. It seems interferon-βworked on nevus cells and led the nevocytes to secrete cytokines such as IL-8. A possibility that there is one pathway on anti-tumor effects related to melanin-prpducing cells, via the neutrophils, is suggested.
- Yamaguchi University Graduate School of Medicineの論文
著者
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MOGAMI Satoshi
Department of Dermatology, Yamaguchi University School of Medicine
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ASAGAMI Chidori
Ohji Hospital
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Okimura Hiroshi
Department of Dermatology, Yamaguchi University School of Medicine
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Muto Masahiko
Department of Dermatology, Yamaguchi University School of Medicine
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