OS1005 間接組織再生のための積層構造SCAFFOLDの圧縮変形挙動(OS10-2 ポリ乳酸とブレンドの力学特性,OS-10 医療用高分子系複合材料の構造と力学特性)

概要

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Regeneration of articular tissues such as cartilage and bone has been one of the most important issues in orthopedic tissue engineering. Biodegradable and biocompatible scaffolds play an important role in the regeneration and implantation processes of tissues. An articular tissue usually has a layered structure consisting of a soft tissue of cartilage and a hard tissue of bone and therefore, scaffolds for articular tissue regeneration need to have multi-layer structures. In the present study, therefore, novel multi-layer scaffolds were developed from biodegrdable polymers such as PCL and PLLA and bioactive ceramics such as hydroxyapatite (HAp). The layered scaffolds consist of a soft layer of porous PCL, a hard layer of PLLA/HAp composite and an interlayer of PCL/PLLA/HAp located between the two layers. Compressive deformation behavior
2011-07-16