強制運動負荷ラットの睡眠覚醒におよぼす酵素処理高麗人参の影響

概要

論文の詳細を見る
Cyclomaltodextrin glucanotransferase-treated Panax Ginseng extract (CG-PGE), which has no bitter taste, was examined for its anti-fatigue effect on exercise-loaded sleep-deprived male rats. Forced locomotion by treadmill for 3 h prior to the dark period resulted in a significant increase in the slow wave sleep (SWS) at the expense of wakefulness (W) during the subsequent 12-h dark period. Oral administrations of 40 mg CG-PGE shortly before and after the exercise prevented the fatigue-derived enhancement of SWS and significantly recovered the amount of nocturnal W. However, latencies to the first episode of SWS and paradoxical sleep were scarcely affected. Similar but insignificant changes were observed after administrations of 20 mg CG-PGE. Thus, it was concluded that CG-PGE exerts an anti-fatigue activity in the presence of stress.
日本生薬学会の論文
1992-09-20