生薬原料「牛黄」の放射線殺菌

概要

論文の詳細を見る
For the application of radio-sterilization to a crude drug "Bezoar Bovis," the radio-resistance of bilirubin and cholic acids which are the characteristic or effective components in Bezoar Bovis was studied in a dose range of 0.01-5 M-Roentgen. When a dry powder sample of Bezoar Bovis was irradiated in a range of 0.01-2 M-Roentgen, bilirubin and cholic acids therein were found to remain intact. The relationship between the mortality of bacteria and fungi adhering to Bezoar Bovis and the radiation dose on them was shown to be of sigmoid type. The complete sterilization dose as 12-D_<10> for those bacteria and fungi adhering to Australian Bezoar Bovis was found to be 1.2 M-Roentgen and 0.6 M-Roentgen respec- tively, and for the bacteria and fungi adhering to South American Bezoar Bovis, 1.1 M-Roentgen and 0.84 M-Roentgen respectively.
日本生薬学会の論文
1981-03-20