Absolute Stereostructure of the Labdane-type Diterpene Alcohol from Alpinia tonkinensis Gagnep
スポンサーリンク
概要
- 論文の詳細を見る
The labdane-type diterpene 15,16-epoxy-8(17),13(16),14-labdatrien-12ξ-ol (1) was isolated together with 2'-hydroxy-4',6'-dimethoxychalcone and 2,3-dihydro-4',7-di-O-methylkaempferol from the rhizomes of the endemic Vietnamese medicinal plant Alpinia tonkinensis Gagnep. (Zingiberaceae). Although both diastereomers of the furanolabdane alcohol 1 provided by the chiral center at the 12-position have already been reported as semisynthetic intermediates, the absolute configuration at the 1 2-position, which affects the chemical shifts of the 1 7-exomethylene protons, remains to be clarified. In this study, the natural furanolabdane 1, which possessed the same ^1H- and ^<13>C-NMR spectroscopic data as those of one of the semisynthetic diastereoisomeric pair, was determined to be in the (12S)-form from spectroscopic data and by applying the modified Mosher's method.
- 日本生薬学会の論文
- 2004-10-20
著者
-
Giang Phan
Faculty Of Chemistry College Of Natural Science Vietnam National University
-
Otsuka Hideaki
Dep. Of Pharmacognosy Graduate School Of Biomedical Sciences Hiroshima Univ. 1-2-3 Kasumi Minami-ku
-
Son Phan
Faculty Of Chemistry College Of Natural Science Vietnam National University
-
Otsuka Hideaki
Graduate School Of Biomedical Sciences Hiroshima University
-
Son Phan
Vietnam National Univ. Hanoi Vnm
-
Giang Phan
Vietnam National Univ. Hanoi Vnm
-
Otsuka Hideaki
Graduate School of Biomedical and Health Sciences, Hiroshima University
関連論文
- Nicorandil, a Potassium Channel Opener and Nitric Oxide Donor, Improves the Frequent Urination without Changing the Blood Pressure in Rats with Partial Bladder Outlet Obstruction(Pharmacology)
- Tricalysionoside A, a Megastigmane Gentiobioside, Sulfatricalysines A—F, and Tricalysiosides X—Z, ent-Kaurane Glucosides, from the Leaves of Tricalysia dubia
- Anti-staphylococcal activity of ent-kaurane-type diterpenoids from Croton tonkinensis
- New Diarylheptanoids from Amomum muricarpum ELMER
- New Megastigmane Glucosides from Excoecaria cochinchinensis LOUR. var. cochinchinensis
- New Bis-spirolabdane-Type Diterpenoids from Leonurus heterophyllus Sw.
- New Diarylheptanoids from Alpinia pinnanensis
- New Labdane-Type Diterpenoids from Leonurus heterophyllus Sw.
- Cytotoxic Diterpenoids from Vietnamese Medicinal Plant Croton tonkinensis GAGNEP
- ent-Pimarane-Type Diterpenoids from Siegesbeckia orientalis L.
- Absolute Stereostructure of the Labdane-type Diterpene Alcohol from Alpinia tonkinensis Gagnep
- Four ent-Kaurane-Type Diterpenoids from Croton tonkinensis GAGNEP.
- A new phenolic glucoside from an Uzbek medicinal plant, Origanum tyttanthum
- Lignan and neolignan glucosides, and tachioside 2'-O-4"-O-methylgallate from the leaves of Glochidion rubrum
- Tricalysiosides P-U : Ent-kaurane Glucosides and a Labdane Glucoside from Leaves of Tricalysia dubia OHWI
- Chemical constituents of an Uzbek medicinal plant, Perovskia scrophularifolia
- Chemical constituents of the essential oil from the bark of Cinnamomum illicioides A. Chev. from Vietnam
- New Neolignans and Lignans from Vietnamese Medicinal Plant Machilus odoratissima NEES
- Absolute Stereostructure of the Labdane-type Diterpene Alcohol from Alpinia tonkinensis Gagnep
- Gallates of isoorientin and (2S)-1,2-propanediol glucoside from the leaves of Schoepfia jasminodora
- A glycerol α-D-glucuronide and a megastigmane glycoside from the leaves of Guettarda speciosa L.
- Three new aliphatic glycosides from the leaves of Antidesma japonicum Sieb. et Zucc.
- Eight New Diterpenoids and Two New Nor-Diterpenoids from the Stems of Croton cascarilloides
- A condensed phenylpropanoid glucoside and pregnane saponins from the roots of Hemidesmus indicus
- Schoepfiajasmins A–H: C-Glycosyl Dihydrochalcones, Dihydrochalcone Glycoside, C-Glucosyl Flavanones, Flavanone Glycoside and Flavone Glycoside from the Branches of Schoepfia jasminodora