The effects of adrenal androgens on glucose metabolism of genetically diabetic mice (db/db) -differences between dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEA-S)-
スポンサーリンク
概要
- 論文の詳細を見る
We investigated the effects of DHEA and DHEA-S on glucose metabolism using diabetic mice db/db in vivo. The DHEA-S-treated mice showed more prominent hepatomegaly and a greater decrease of the serum glucose level than DHEA-treated mice. These preliminary data suggest that DHEA-S has a stronger hypoglycemic effect than DHEA, or even that the hypoglycemic effect may be due to DHEA-S, rather than DHEA. The modes of action of DHEA and DHEA-S in diabetic mice should be evaluated from the perspective that these steroids have distinct effects, that can contribute to clarifying the basic pathogenesis of diabetes mellitus.
- 藍野大学の論文
著者
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Hanafusa Toshiaki
Department Of First Internal Medicine Osaka Medical College
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Ohsawa Nakaaki
School Of Nursing And Aino Institute For Aging Research Aino Gakuin College
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Hanafusa Toshiaki
Department Of Internal Medicine (i) Osaka Medical College
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Maeda Tamaki
Department Of Chemistry And Bioscience Faculty Of Science Kagoshima University
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Tanaka Toshifumi
Department Of Internal Medicine Hanwa Hospital
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KOYAMA Akio
Aino Gakuin
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Takagaki Masao
School Of Nursing And Aino Institute For Aging Research Aino Gakuin College And Department Of Neuros
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Sakai Reiko
School Of Nursing And Aino Institute For Aging Research Aino Gakuin College
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SAKAI Reiko
Department of Nursing, Faculty of Nursing, Aino Gakuin College, Aino Institute for Aging Research
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FURUTAMA Daisuke
Department of Internal Medicine (I), Osaka Medical College
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FUJIMURA Chieko
Department of Internal Medicine (I), Osaka Medical College
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OHSAWA Nakaaki
Department of Nursing, Faculty of Nursing, Aino Gakuin College, Aino Institute for Aging Research
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Ohsawa Nakaaki
Department Of Nursing Faculty Of Nursing Aino Gakuin College Aino Institute For Aging Research
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Sakai Reiko
Department Of Nursing Faculty Of Nursing Aino Gakuin College Aino Institute For Aging Research
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Tanaka Toshifumi
Department Of Civil Engineering Graduate School Of Engineering Kobe University
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Furutama Daisuke
Department Of Internal Medicine (i) Osaka Medical College
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Fujimura Chieko
Department Of Internal Medicine (i) Osaka Medical College
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TANAKA Toshifumi
Department of Nursing, Faculty of Nursing, Aino Gakuin College, Aino Institute for Aging Research
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MAEDA Tamaki
Department of Nursing, Faculty of Nursing and Rehabilitation, Aino University
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