Penicillin biosynthesis in Aspergillus oryzae and its overproduction by genetic engineering(GENETICS, MOLECULAR BIOLOGY, AND GENE ENGINEERING)
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概要
- 論文の詳細を見る
Aspergillus oryzae penicillin biosynthetic genes were clustered. The penicillin production was positively regulated by VeA, a global gene regulator required for transcriptional expression of the penicillin biosynthetic genes. Overexpression of the biosynthetic genes by a strong promoter yielded a greater than 100-fold increase in penicillin production.
著者
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Ohashi Shinichi
Genome Biotechnology Laboratory, Kanazawa Institute of Technology
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Marui Junichiro
Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Techn
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Ohashi-Kunihiro Sumiko
Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Techn
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Ando Tomohiro
Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Techn
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Nishimura Marie
Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Techn
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Koike Hideaki
Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Techn
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Machida Masayuki
Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Techn
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Ando Tomohiro
Research Institute For Cell Engineering National Institute Of Advanced Industrial Science And Techno
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Marui Junichiro
Research Institute For Cell Engineering National Institute Of Advanced Industrial Science And Techno
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Koike Hideaki
Research Institute For Cell Engineering National Institute Of Advanced Industrial Science And Techno
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Nishimura Marie
Research Institute For Cell Engineering National Institute Of Advanced Industrial Science And Techno
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Ohashi-kunihiro Sumiko
Research Institute For Cell Engineering National Institute Of Advanced Industrial Science And Techno
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Machida Masayuki
Research Institute For Cell Engineering National Institute Of Advanced Industrial Science And Techno
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Ohtaki Shinsaku
Laboratory Of Molecular Enzymology Division Of Life Science Graduate School Of Agricultural Science
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Machida Masayuki
Research Institute For Cell Engineering National Institute Of Advanced Industrial Science And Techno
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