鼻アレルギーのレーザー治療

概要

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A carbon dioxide (CO_2) laser was applied in treating the hypertrophic inferior turbinates of patients with nasal congestion due to allergy as a day surgery, and good results were obtained, not only with nasal stuffiness, but also with hyperrhinorrhea and sneezing at Tokyo Women's Medical University Hospital since 1988. Treatment involved 10～14 watts for 0.5 second of a defocused pulse beam of a CO_2 laser fitted with special handpieces. In patients with nasal allergies, the allergic reaction occurs in the epithelium and the superficial submucosa, the target area of the CO_2 laser technique the author employed. Light microscopy showed regeneration of the ciliated epithelium one month after the procedure, which was consistent with the saccharin test. Laser surgery diminished the quantity of nasal glands in the superficial submucosa and the number of goblet cells in the regenerated epithelium. New collagen fibers in the superficial submucosa were noted one month after laser turbinate surgery. The irradiated tissues of the turbinate were thought to have lost their ability to swell, due to the formation of collagen fiber net. And it suggested that the collagen fiber net may have blocked both the invasion of allergens to the venous plexus and the exudation of mast cells to the epithelium, thus suppressing the allergic reaction.
東京女子医科大学の論文
2000-07-25