新生児早期における心拍変動の解析

概要

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The study examined the relationship between heartbeat and respiration of early neonates in the first 3 days after birth. Subjects were 46 delivered neonates from normal pregnancies, of whom 15 and 31 were examined on the day they were born and 1-3 days after birth, respectively. Their weights at the birth were over 2,500 g and their Apgar score were 8 to 10 points with good health and normal appearance. The following results were obtained. About 1h after birth, R-R intervals and respiration periods significantly decreased (p<0.05); the heart-beat rhythm stabilized; the spectral gradient of heartbeat 1/f^n fluctuation also decreased significantly (p<0.05); and there were no apparent frequency peaks in coherence between heartbeat and respiration. About 5h after birth, R-R intervals increased gradually and the spectral gradient of heartbeat 1/f^n fluctuation recovered. Respiratory frequency components were also clearly found with coherence between heartbeat and respiration. Based on these it was concluded that, in healthy and normal early neonates, the R-R interval decreases about one hour after the birth in conjunction with reductions in heartbeat variation related to respiration.