EXPERIMENTAL STUDIES ON SURGICAL TREATMENT OF ACUTE MYOCARDIAL INFARCTION WITH SPECIAL REFERENCE TO THE EVALUATION OF INFARCTECTOMY AND ITS SAFETY

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For surgical treatment of acute myocardial infraction, infarctectomies are frequently used because indication of the reconstruction of coronary circulation is restricted. In order to increase safety and the amounts of resectable myocardium in the treatment of acute myocardial infarction, an experiment was performed in which infarction was induced by multiple ligation of the left ventricular free walls in mongrel adult dogs so as to investigate hemodynamics, serum-biochemical, and serum-enzymic changes. When the weight of removable myocardium was over 11.5% of the whole myocardial weight, many dogs died due to right cardiac failure. The cause of the death may be in the imbalance between left and right cardiac outputs resulting from narrowing of the left ventricular cavity. In order to decrease the loads imposed upon right heart and pulmonary circulatory systems, the inferior vena cava were constricted after the infarctectomy. As a result, the infarctectomy with limitation of the venous return increased the weights of the removable myocardium up to 13.5%. Furthermore, when the resected weights were 12% or less, all the dogs survived, and hemodynamic and serum-enzymic values recovered up to 80% of their level before the induction of acute myocardial infarction. Clinically, infarctectomy with limitation of the venous return is a useful and safe method for removing myocardial infarction, and is easy and simple to perform. It can easily and safety be performed by inserting a catheter with a balloon in to the inferior vena cava. So this method can be used for removing larger amounts of myocardium.
名古屋市立大学の論文
1977-11-28

EXPERIMENTAL STUDIES ON SURGICAL TREATMENT OF ACUTE MYOCARDIAL INFARCTION WITH SPECIAL REFERENCE TO THE EVALUATION OF INFARCTECTOMY AND ITS SAFETY

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