SERUM BILE ACID COMPOSITION IN FULMINANT HEPATITIS. COMPARATIVE STUDY WITH ACUTE HEPATITIS

概要

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The serum bile acids of fulminant hepatitis 24 h after the onset of grade II-III encepalopathy were analyzed by high performance liquid chromatography in comparison with those of critical acute hepatitis. The total bile acid level tended to be low in cases of fulminant hepatitis as compared to the cases of acute hepatitis. Regarding the bile acid composition, a decrease in the cholic acid and an increase in the chenodeoxycholic acid were observed in cases of fulminant hepatitis as compared to the cases of acute hepatitis. An increase in the glycine conjugated bile acids and a decrease in the taurine conjugated bile acids were observed in the cases of fulminant hepatitis. In one surviving case of fulminant hepatitis, however, the taurine conjugated forms were kept relatively high and the level was close to that in acute hepatitis.
名古屋市立大学の論文
1984-07-24