P1-45 ナノ微粒子造影剤を用いたマイクロバブル生成に関する検討(ポスター発表)

概要

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For tumor detection and therapy with ultrasound, we are proposing the use of nano-sized liquid precursor of microbubbles, which is small enough to accumulate in tumor tissues and generate microbubbles with ultrasound pulses. Although ultrasonic signal intensity changes are seen when triggering ultrasound pulse is exposed, until now, no direct evidence that microbubble generation induced the ultrasonic changes. This time we developed a experimental setup for simultaneous ultrasonic and optical observation of gels containing nano-sized liquid precursors. It was found that the acoustic intensity threshed to induce ultrasonically significant changes by triggering pulse is the same as that to induce optically significant changes. Our results suggest the changes in ultrasonic images on the triggering ultrasound is due tothe generation of microbubbles.
超音波エレクトロニクスの基礎と応用に関するシンポジウム運営委員会の論文
2006-11-15