P-47 ハイドロキシアパタイト/コラーゲン複合体膜から作製した連通性多孔体による骨再生(インプラント,一般講演(ポスター発表),第54回日本歯科理工学会学術講演会)

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The authors have developed novel Hydroxyapatite/Collagen(HAp/Col) nanocomposite with similar nanostructure and chemical composition to bone and demonstrated the HAp/Col is incorporated into bone remodeling process. In the present study, unidirectional porous device with the advantageous space for bone regeneration is made by rolled up to HAp/Col membrane and investigated its bone regeneration ability in in vivo. The unidirectional porous HAp/Col devices were able to stimulate bone regeneration for the critical bone defect of dogs. Consequently, in the mechanical property of bone regeneration devices, the unidirectional porous with the space of the size which can regenerate bone tissue was required.
2009-09-10