内科的諸疾患に於ける血清鉄,特に腎疾患に於ける血清鉄に就いての研究
スポンサーリンク
概要
- 論文の詳細を見る
For the purpose of contributing to the research on iron metabolism in kidney troubles, the author carried out studies on the whole blood iron level, serum iron level, plasma total protein value, plasma protein fraction value and the influence of oral administration of iron in patients afflicted with kidney troubles. The results obtained were compared to those obtained in the similar experiments performed in the patients suffering from anemia and hepatic troubles. 1) Whole blood ironlevel in kidney troubles showed similar decrease from the normal value as that manifested in hepatocirrhosis and malignant tumors. It was noted that some patients with kidney troubles showed a further decrease attendant with the exacerbation of clinical symptoms. A decrease in whole blood iron level was also observed in essential hypochromic anemia, hookworm anemia and hemorrhagic anemia. 2) Serum ironlevl in the above-mentioned three forms of anemia was lower than the normal value. It was higher than the normal value in acute hepatitis and hemolytc jaundice, while it remained within the lower limit of the normal range in cholelithiasis. It was higher in hepatocirrhosis than in cancer of the liver and other malignant tumors. 3) There was more or less similar tendency in the values of serum iron and whole blood iron in essential hypochromic anemia and hookworm anemia. The same did not necessarily hold true of those values in kidney troubles and other diseases. 4) There was no correlation between serum iron level and plasma total protein value. Nor was there any such relation between the serum iron level and plasma protein fraction value in kidney troubles. 5) Serum iron level was generally lower than the normal value in most of the patients with kidney troubles. It showed a tendency to decrease keeping pace with the. worsening in renal function insufficiency. A study of the influence of orally administered iron has revealed the presence of hindrance to the absorption of iron in patients with kidney troubles. Low serum iron level with concomitant increase in the amount of protein excreted in the urine was observed in most of those patients. There was no uniform pattern of relation between serum iron level and non-protein nitrogen value for those patients. Serum iron level showed a tendency to rise from low level in uremia. 6) The results of the present studies would indicate that of all the factors involved, the presence of hindrance to the absorption of iron as well as the excretion of serum iron bound to protein in the urine is mainly responsible for the low serum iron level in kidney troubles.
- 千葉大学の論文
著者
関連論文
- 千葉県下某地区全住民の結核集団検診よりみた胸部非結核性異常影の実態に就て
- 20. 農村結核集団検診より得た2,3の知見(第34回千葉医学会総会講演要旨)
- 2. 近隣町村に於ける胃集団検の精密検査成績(第405回千葉医学会例会 三輪内科例会)
- 内科的諸疾患に於ける血清鉄,特に腎疾患に於ける血清鉄に就いての研究
- 11) 当教室に於けるアイソトープに関する中間報告(千葉医学会第30回総会,昭和28年度千葉県医師会医学会連合大会)