Increased Corneal Thickness and Associated Factors After Laser in situ Keratomileusis

概要

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The aim of this study is to investigate changes in central corneal thickness (CCT) and to detect any associated factors after laser in situ keratomileusis (LASIK). The charts of 46 patients who had undergone bilateral LASIK were retrospectively reviewed. The postoperative changes in CCT were measured until 6 months postoperatively and the relation between CCT increases and other clinical factors was investigated. The factors analyzed were age, gender, preoperative CCT, ablation depth, ablation ratio, refractive regression, and development of diffuse lamellar keratitis (DLK). The CCT significantly increased from 1 week to 6 months postoperatively. Age, preoperative CCT, refractive regression, and development of DLK were not correlated with increased CCT. The CCT increase was greater in women than in men. The ablation depth and the ablation ratio were significantly positively correlated with increased CCT (r=0.544, P<0.0001 and r=0.539, P<0.0001, respectively). The increase in CCT was greater in corneas that underwent more tissue ablation. Accurate CCT evaluation is important for LASIK enhancement to avoid the postoperative keratectasia by overestimating the corneal pachymetry.