Postoperative Treatment With Carvedilol, a β-Adrenergic Blocker, Prevents Paroxysmal Atrial Fibrillation After Coronary Artery Bypass Grafting
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概要
- 論文の詳細を見る
Background Arrhythmias following cardiovascular surgery lead to unstable hemodynamics, along with myocardial ischemia and decreased cardiac output. The purpose of the present case cohort study compared the control group with no carvedilol administered and the other group of patients given carvedilol and determined whether postoperative treatment with carvedilol, a β-adrenergic blocker, prevents paroxysmal atrial fibrillation after coronary artery bypass grafting (CABG). Methods and Results Of 160 patients who underwent scheduled isolated CABG, 80 received postoperative carvedilol and 80 did not. Postoperative paroxysmal atrial fibrillation was defined as episodes of atrial fibrillation persisting for over 10 min and confirmed by 12-lead electrocardiography. The incidence of paroxysmal atrial fibrillation was significantly lower in patients given carvedilol (12/80:15%) than in those who were not (27/80:34%) (p=0.0094). Logistic regression analysis showed that only postoperative carvedilol was significantly associated with the development of postoperative atrial fibrillation (95% confidence interval, 0.169-0.832; p=0.0159). Conclusion Postoperative treatment with carvedilol prevented paroxysmal atrial fibrillation after CABG.
- 社団法人日本循環器学会の論文
- 2008-03-20
著者
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OKABAYASHI HITOSHI
Department of Cardiovascular Surgery
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Tsuboi Junichi
Department of Cardiovascular Surgery, Iwate Medical University
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Tsuboi Junichi
Department Of Cardiovascular Surgery Iwate Medical University Memorial Heart Center
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Kawazoe Kohei
Department of Cardiovascular Surgery, National Cardiovascular Center
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Kawazoe Kohei
Department Of Cardiovascular Surgery Iwate Memorial Heart Center
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Kawazoe Kohei
Department Of Cardiac Surgery. National Cardiovascular Center Hospital
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IZUMOTO HIROSHI
Department of Cardiovascular Surgery, Iwate Medical University Memorial Heart Center, Iwate Medical
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Izumoto Hiroshi
Department Of Cardiovascular Surgery Akita University School Of Medicine
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Kawazoe Kohei
Third Department Of Surgery Iwate Medical University
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Okabayashi Hitoshi
Department Of Cardiovascular Surgery Iwate Medical University Memorial Heart Center
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Okabayashi Hitoshi
Department Of Cardiology Thoracic Surgery
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Kawazoe Kohei
Committee On Guideline For Prevention And Management Of Infective Endocarditis Japanese Circulation
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Izumoto Hiroshi
Department Of Cardiovascular Surgery Akita University
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OKABAYASHI Hitoshi
Department of Cardiovascular Surgery, Iwate Medical University, Memorial Heart Center
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Okabayashi Hitoshi
Department of Cardiac Surgery, Iwate Medical University
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Tsuboi Junichi
Department of Cardiac Surgery, Iwate Medical University
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