In-vitro and Clinical Evaluation of Cardiac Valve Substitutes : PANEL DISCUSSION ON VARIOUS PROBLEMS IN VALVE REPLACEMENT
スポンサーリンク
概要
- 論文の詳細を見る
One of the major causes of postoperative morbidity and mortality after valve replacement surgery is the prosthetic valve substitute itself. In this discussion, therefore, we make a fundamental evaluation of hydrodynamic valve function and present our clinical results following valve replacement with the Bjork-Shiley valve prosthesis, the Hancock porcine xenograft and the Ionescu-Shiley bovine pericardial xenograft. In an experimental study using a mechanical simulator system, the pericardial xenograft displayed superior hydrodynamic characteristics compared to other two valve subdtitutes. Postoperative hemodynamic evaluation further indicated that the pericardial xenograft performed significantly better than the porcine xenograft regarding transvalvular pressure gradient, effective valve area and cusp opening. In addition, data from 387 patients with aortic, mitral or both types of valve replacement who had received one of the three kinds of valve substitute were analyzed. Systemic thromboembolic complications occurred in one patient with an aortic Bjork-Shiley valve (0.6% per patient-year), six with mitral Hancock xenografts (2.2% per patient-year) and one with an aortic and mitral Hancock xenograft (2.2% per patient-year). The incidence of prosthetic valve endocarditis was 0.84% per patient-year for the Hancock xenograft and 1.84% per patient-year for the Ionescu-Shiley xenograft. It was concluded that the hemodynamic and antithrombogenic advantages of the pericardial xenograft proven by our mid-term follow-up study make it the valve substitute of choice. However, careful attention is required regarding prosthetic valve endocarditis tissue heart valves, which are more susceptible to infection than mechanical ones, and the long-term durability of the pericardial xenograft remains to be confirmed.
- 社団法人日本循環器学会の論文
- 1984-10-20
著者
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Fujuta Tsuyoshi
Department Of Cardiovascular Surgery National Cardiovascular Center
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Fujita Tsuyoshi
Department Of Cardiology Tokyo Women's Medical Univercity
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Hori M
Hyogo University Of Health Sciences
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Ohara Kuniyoshi
Department of Thoracic and Cardiovascular Surgery, Kitasato University School of Medicine
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Kawazoe Kohei
Department of Cardiovascular Surgery, National Cardiovascular Center
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Fujita Tsuyoshi
Department Of Cardiovascular Surgery National Cardiovascular Center
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Fujita Tsuyoshi
Dept. Of Surgery National Cardiovascular Center
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Ohara Kuniyoshi
Department Of Thoracic And Cardiovascular Surgery Kitasato University School Of Medicine
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Ohara Kuniyoshi
北里大学 医学部胸部外科学
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Ohara Kuniyoshi
北里大学 胸部心臓血管外科
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Kawazoe Kouhei
Department of Cardiovascular Surgery National cardiovascular Center
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Manabe Hisao
Department of Cardiovascular Surgery National Cardiovascular Center
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Kawazoe Kohei
National Cardiovascular Center Division Of Cardiology
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Kawazoe Kohei
Department Of Cardiovascular Surgery National Cardiovascular Center
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TOMINO TETSUO
Department of the Cardiovascular Surgery and the Cardiology of the National Cardiovascular Center
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Tomino Tetsuo
Department Of Cardiovascular Surgery And Department Of Artifitial Organ National Cardiovascular Cent
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UMEZU Mitsuo
Department of Mechanical Engineering, Waseda University
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Kawazoe Kohei
Department Of Cardiac Surgery. National Cardiovascular Center Hospital
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Umezu Mitsuo
Department Of Cardiovascular Surgery And Department Of Artifitial Organ National Cardiovascular Cent
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Tatsumi Fujio
Department Of Cardiorogy The Heart Institute Of Japan Tokyo Women's Medical University
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Fujita Tsuyoshi
The Department Of Cardiovascular Surgery National Cardibvascular Center
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Tatsumi Fujio
Department Of Cardiology Tokyo Women's Medical Univercity
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KAKU KATSUHIKO
Department of Cardiovascular Surgery and Department of Artifitial Organ, National Cardiovascular Cen
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Tomlno Tetsuo
Department Of Cardiovascular Surgery National Cardiovascular Center
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Kaku Katsuhiko
Department Of Cardiovascular Surgery National Cardiovascular Center
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Kaku Katsuhiko
Department Of Cardiovascular Surgery And Department Of Artifitial Organ National Cardiovascular Cent
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Ohara Kuniyoshi
Divisioh Of Cardiac Surgery National Cardiovascular Center
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Ohara Kuniyoshi
Department Of Cardiovascular Surgery Kitasato University School Of Medicine
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Takao Tetsuji
1st Dept. Of Surg. Osaka Univ. Med. School
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Matsuda Hikaru
Department Of Cardiology Osaka University Graduate School Of Medicine
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Fujita Tsuyoshi
Department Of Cardiology The Heart Institute Of Japan Tokyo Women's Medical University
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Manabe Hisao
Department Of Cardiac Surgery National Cardiovascular Center
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Kaku Katsuhiko
First Department Of Surgery Osaka University Hospital
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Kawazoe Kouhei
Departments Of Cardiovascular Surgery And Cardiology National Cardiovascular Center
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Kawazoe Kohei
国立循環器病センター研究所
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Fuiita Tsuyoshi
Department Of Cardiology Tokyo Women's Medical Univercity
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Oki Katsuyoshi
The Heart Instltute Japan Tokyo Women's Medical College
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Manabe Hisao
Department Of Cardiovascular Surgery And Department Of Artifitial Organ National Cardiovascular Cent
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Kaku Katsuhiko
Department Of Cardiovascular Surgery And Department Of Artifitial Organ National Cardiovascular Cent
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Kaku Katsuhiko
Department Of Cardiovascular Surgery And Department Of Artifitial Organ National Cardiovascular Cent
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Fujita Tsuyoshi
Divisioh Of Cardiac Surgery National Cardiovascular Center
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Fujita Tsuyoshi
Department Of Cardiac Surgery. National Cardiovascular Center Hospital
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