744 肌のシワに対する真皮老化の影響に関する数値解析的検討(S08-4 細胞の構造とメカノバイオロジー(4),S08 細胞の構造とメカノバイオロジー)

概要

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We investigate the effect of dermal aging on the wrinkle property of human facial skin. Wrinkle property is evaluated by the finite element buckling analysis considering the layered structure of skin. The solar elastosis, which is a result of the photoaging and increases abnormal elastic fibers in the papillary dermis, has been thought as a major cause of the formation of permanent wrinkles on facial skin. Moreover, from the mechanical standpoint, the flattening of dermal-epidermal junction caused by the intrinsic aging may also affect the permanent wrinkle formation. Through some numerical examples, we discuss the effect of the thickness change of papillary dermis and the shape alteration of dermal-epidermal junction on the wrinkle property, and approach to a reliable scenario of the wrinkle formation mechanism.
一般社団法人日本機械学会の論文
2006-09-15