727 水中平面衝撃波による培養内皮細胞への影響 : 圧力波形の影響と遺伝子発現による増殖能解析(S08-1 細胞の構造とメカノバイオロジー(1),S08 細胞の構造とメカノバイオロジー)

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In this paper, to investigate the effects of shock waves on the endothelial cells in vitro, Gene expression of the cells by plane shock waves are measured by Real-Time PCR. After working shock waves on suspended cells, Quantity of growth factor are increased. It is shown that the growth rate of suspended endothelial cells are accelerated by plane shock waves. To clarify these stimulation on the cell, shock wave propagation is investigated into cell by finite element method. The result show that, a high shear stress is caused by the shock wave in the cell membrane, and the frequency and the amplitude of the maximum shear stress is increased when the rise time of the shock wave is small.
2006-09-15