イオン泳動効果のMRIテンソル表示(<特集>生体医工学シンポジウム2007)

概要

論文の詳細を見る
The goal of this study is to make active or passive electrical characteristics of biological systems visible by magnetic resonance imaging (MRI). As a starting investigation, we visualized a precise flow effected by ionophoresis. We used CuSO_4 doped water (25mM) electrolytes in an ionophoresis cell composed of a pair of horizontal copper electrodes. An evaluation of ion drift, we made by MR diffusion tensor imaging method. The impressed voltage was 0.0-0.5V, and the current density at that time increased monotonously was 0.00-1.06mA/cm^2. With increasing current density, higher values of drift diffusion coefficient (DDC) induced by the electric field were observed. The diffusion tensor ellipsoid in current density of 1.06mA/cm^2 was successfully visualized as the effects of ion drift induced by the electric field. By applying this method to biological systems, it has a possibility to make functional electrical characteristics visible.
社団法人日本生体医工学会の論文
2007-12-10