Microbial Hydroxylation of 2-Phenylpropionic Acid(Biological Chemistry)
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概要
- 論文の詳細を見る
The hydroxylation of 2-phenylpropionic acid (PPH) to 2-(p-hydroxyphenyl)propionic acid (HPPH) was investigated using various microorganisms. The highest hydroxylating activity was found in Streptoinyces rimosus ATCC 10907. The reaction product was isolated and identified as 2-(p-hydroxyphenyl)propionic acid, which had no specific rotation, indicating that the reaction was not stereoselective at the benzylic position. In a 5-1 jar fermentor containing a medium consisting of 2% sorbitol, 2% soybean meal, and 1% malt extract (pH 7.2), the conversion rate from 0.2% of PPH reached 60% using a PPH-resistant mutant, KY-661-18.
- 社団法人日本農芸化学会の論文
- 1991-04-23
著者
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UWAJIMA TAKAYUKI
Faculty of Engineering, Fukui University
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UWAJIMA Takayuki
Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd.
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Mochida K
Marine Biotechnol. Inst. Co. Ltd. Iwate Jpn
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KUGE Yukihiro
Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd.
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MOCHIDA Kenichi
Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd.
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Kuge Yukihiro
Sakai Research Laboratories Kyowa Hakko Kogyo Co. Ltd.
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Uwajima T
Faculty Of Engineering Fukui University
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Uwajima Takayuki
Tokyo Research Laboratories Kyowa Hakko Kogyo Co. Ltd.
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