Enhancing Effect of Indigocarmine on the Mutagenicity of Trp-P-1 in the Salmonella/Microsome(Food & Nutrition)

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概要

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• The effects of artificial food dyes on the mutagenicity of carcinogenic mutagens were examined using the Salmonella/microsome system. Indigocarmine (IC), an indigoid dye widely used for coloring foods and for clinical tests, enhanced the mutagenic activity of Trp-P-1, a carcinogenic pyrolysate of tryptophan, depending on the dose of IC. His^+ revertants of TA 98 induced by Trp-P-1 were two to four times greater in the presence of 10 to 50 μg/plate of IC than those in the absence of IC. IC also enhanced the mutagenicity of Trp-P-2, another carcinogenic pyrolysate of tryptophan, while the activities of other mutagens such as MNNG, 4-NQO, AF-2, BP, Glu-P-1 were not affected.

• 社団法人日本農芸化学会の論文
• 1988-11-23

著者

• Tomita Yoshifumi

  Department Of Internal Medicine And Cardiology Nippon Medical School Tama-nagayama Hospital

• Tomita Yoshifumi

  Department Of Public Health School Of Medicine Kurume University

• Tomita Yoshifumi

  Department Of Cardiology Tamanagayama Hospital Nippon Medical School

• YAMADA Jiro

  Faculty of Education, Yamaguchi University

• FUKUDA Katuhiro

  Department of Public Health, School of Medicine, Kurume University

• Fukuda K

  Kyushu Univ. Fukuoka Jpn

• Yamada Jiro

  Faculty Of Education Yamaguchi University

関連論文

• Pathophysiological Analysis of Serum Troponin T Release Kinetics in Evolving Ischemic Myocardial Injury
• Isolation and Identification of Sphingomonas sp. That Yields tert-Octylphenol Monoethoxylate under Aerobic Conditions
• Enhancing Effect of Indigocarmine on the Mutagenicity of Trp-P-1 in the Salmonella/Microsome(Food & Nutrition)
• Effects of trialkyltin chlorides on Escherichia coli spheroplasts.

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