Sex Inversion of Sexually Immature Honeycomb Grouper(Epinephelus merra) by Aromatase Inhibitor(Reproductive Biology)
スポンサーリンク
概要
- 論文の詳細を見る
Previous studies have shown that estrogen plays an important role in sex change of protogynous honeycomb grouper, and that the treatments with aromatase inhibitor (Al) cause estrogen depletion and complete sex inversion of pre-spawning females into functional males. In the present study, we examined whether Al causes sex inversion of sexually immature females. Female honeycomb groupers were implanted with various doses of Fadrozole (0, 100, 500 and 1000 μg/fish) in the non-breeding season, and resultant changes in the gonadal structures and the plasma levels of sex steroid hormones (estra-diol-17β, E2; testosterone, T; 11-ketotestosterone, 11-KT) were examined three months after implantation. Vehicle-implanted groups did not change sex, while 100 and 500 μg Al-implanted groups had turned into transitionals with intersex gonad. In contrast, the highest dose receiving group exhibited both transitional and male phases. Transitional phase gonad had atretic oocytes and spermatogenic germ cells at the late stages of spermatogenesis, while male phase testis contained spermatozoa accumulated in the seminiferous tubules. All males released sperm upon slight pressure on the abdomen. In the Al-implanted fish, plasma levels of E2 decreased in a dose-dependent manner, while the levels of 11-KT were high in the highest dose receiving group. Present results suggest that estrogen plays an important role in sex change of protogynous honeycomb grouper, and that treatments with Al potentially inhibits endogenous E2 production in vivo, causing oocyte degeneration and subsequently the sex inversion from female to male. The Fadrozole could be an important tool for manipulating the sex of hermaphrodite fishes.
- 社団法人日本動物学会の論文
- 2004-03-25
著者
-
Bhandari Ramji
Sesoko Station Tropical Biosphere Research Center University Of The Ryukyus
-
Bhandari R
Field Science Center For Northern Biosphere Hokkaido University
-
Nakamura Masaru
Sesoko Station, Tropical Biosphere Research Center, University of the Ryukyus
-
Bhandari Ramji
Sesoko Station Tropical Biosphere Res. Center Univ. Of The Ryukyus
-
Komuro Hiroki
Sesoko Station, Tropical Biosphere Research Center, University of the Ryukyus
-
Higa Mikihiko
Sesoko Station, Tropical Biosphere Research Center, University of the Ryukyus
-
中村 將
Sesoko Station Tropical Biosphere Research Center University Of Ryukyus
-
Komuro Hiroki
Sesoko Station Tropical Biosphere Research Center University Of The Ryukyus
-
Higa M
Sesoko Station Tropical Biosphere Research Center University Of The Ryukyus
-
Nakamura Masaru
Sesoko Station Tropical Biosphere Research Center University Of The Ryukyus
関連論文
- A POSSIBLE ROLE OF STEROIDAL SUBSTANCES EXISTING IN THE ABDOMINAL GLAND OF THE MALE NEWT, CYNOPS PYRRHOGASTER(Endocrinology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
- OCCURRENCE OF STEROIDAL SUBSTANCES IN THE ABDOMINAL GLAND OF THE NEWT CYNOPS PYRRHOGASTER(Endocrinology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
- Seasonal Variation in the Expression of Five Subtypes of Gonadotropin-releasing Hormone Receptor Genes in the Brain of Masu Salmon from Immaturity to Spawning
- EFFECTS OF GnRHa ON EXPRESSION OF GENES ENCODING GONADOTROPIN SUBUNITS AND GROWTH HORMONE/PROLACTIN/SOMATOLACTIN IN THE PITUITARY OF MASU SALMON(Endocrinology)(Proceedings of the Seventy-Third Annual Meeting of the Zoological Society of Japan)
- Induction of Female-to–male Sex Change in the Honeycomb Grouper (Epinephelus merra) by 11-ketotestosterone Treatments
- A FEMALE-ATTRACTING ACTIVITY OF STEROIDAL SUBSTANCES IN THE ABDOMINAL GLAND OF THE MALE NEWT, CYNOPS PYRRHOGASTER
- SYNTHESIS OF STEROIDAL SUBSTANCES IN THE ABDOMINAL GLAND OF THE NEWT CYNOPS PYRRHOGASTER
- Sex Inversion of Sexually Immature Honeycomb Grouper(Epinephelus merra) by Aromatase Inhibitor(Reproductive Biology)
- FUNCTIONAL SEX REVERSAL AFTER OVARIAN DIFFERENTIATION IN THE GONOCHORISTIC FISH, NILE TILAPIA : ENDOCRINE CHANGES(Endocrinology,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
- FUNCTIONAL SEX REVERSAL BY THE TREATMENT OF AROMATASE INHIBITOR AFTER OVARIAN DIFFERENTIATION IN TILAPIA(Endocrinology,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
- IN VITRO SPERMATOGENESIS IN FISH OVARY(Endocrinology,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
- Gonadal Restructuring and Correlative Steroid Hormone Profiles during Natural Sex Change in Protogynous Honeycomb Grouper (Epinephelus merra)(Endocrinology)
- 飼育環境下におけるマアナゴの卵巣発達と血中ステロイドホルモン量の変化
- Gonadal structure and P450scc and 3β-HSD immunoreactivity in the gobiid fish Trimma okinawae during bidirectional sex change
- Gonadal structure of the serial-sex changing gobiid fish Trimma okinawae
- EXPRESSION OF GONADOTROPIN RECEPTORS IN THE SERIAL SEX CHANGING GOBY, TRIMMA OKINAWAE(Endocrinology,Abstracts of papers presented at the 75^ Annual Meeting of the Zoological Society of Japan)
- Characterization of Two Types of Cytochrome P450 Aromatase in the Serial-sex Changing Gobiid Fish, Trimma okinawae
- EXPRESSION OF AD4BP/SF-1 IN RED-SPOTED DWARF GOBY, TRIMMA OKINAWAE, DURING MULTI-SEX CHANGE(Endocrinology,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
- ISOLATION OF TWO P450 AROMATASE cDNAs : THEIR mRNA EXPRESSION DURING SERIAL ADULT SEX CHANGE IN GOBBIID FISH TRIMMA OKINAWAE(Endocrinology & Genetics)(Proceedings of the Seventy-Third Annual Meeting of the Zoological Society of Japan)
- TWO TYPES OF P450 AROMATASE DURING SERIAL ADULT SEX CHANGE IN GOBIID FISH Trimma okinawae : cDNA ISOLATION AND mRNA EXPRESSION
- INTERACTION BETWEEN EGGS AND SPERMATOZOA AMONG FOUR CLOSELY RELATED SPECIES OF SEA URCHINS (GENUS ECHINOMETRA) IN OKINAWA(Developmental Biology,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
- SEX REVERSAL BY AROMATASE INHIBITOR TREATMENT IN THE PROTOGYNOUS WRASSE, HALICHOERES TRIMACULATUS(Endocrinology)(Proceedings of the Seventy-Third Annual Meeting of the Zoological Society of Japan)
- Comparative Studies on the Energy Metabolism in Spermatozoa of Four Closely Related Species of Sea Urchins (Genus Echinometra) in Okinawa(Biochemistry)
- EXPRESSION OF ESTROGEN RECEPTORS AND STEROIDOGENIC ENZYMES DURING GONADAL DIFFERENTIATION IN A TELEOST FISH, TILAPIA NIROTICUS(Developmental Biology)(Proceedings of the Seventieth Annual Meeting of the Zoological Society of Japan)
- 性分化と環境 (特集 魚介類の単性養殖)
- Fish 3β-Hydroxysteroid Dehydrogenase/Δ^5-Δ^4 Isomerase : Antibody Production and Their Use for the Immunohistochemical Detection of Fish Steroidogenic Tissues
- Nonylphenol induces complete feminization of the gonad in genetically controlled all-male amago salmon
- Refractive Indices in Undoped and MgO-Doped Near-Stoichiometric LiTaO_3 Crystals : Optics and Quantum Electronics
- Optical Damage Resistance and Refractive Indices in Near-Stoichiometric MgO-Doped LiNbO_3 : Optics and Quantum Electronics
- Quasi-Phase-Matched Optical Parametric Oscillator Using Periodically Poled MgO-Doped LiNbO_3 Crystal
- Bulk Periodically Poled MgO-doped LiNbO_3 by External Electric Field Application
- THE ROLE OF ANDROGEN IN PROTOGYNOUS SEX CHANGE OF GROUPER
- Sex Change in Fish(In the Line of Descent from an Ansestor-Origin and Differentiation of Germ Cells in Different Phyla-,Symposium,PROCEEDING OF THE 76^ ANNUAL MEETING OF THE ZOOLOGICAL SOCIETY OF JAPAN)
- EXPRESSION OF AROMATASE mRNA IN THE NEWT ABDOMINAL GLAND(Endocrinology,Abstracts of papers presented at the 75^ Annual Meeting of the Zoological Society of Japan)
- IMMUNOLOCALIZATION OF TWO STEROIDOGENIC ENZYMES (P450scc AND P450c11) IN GONADS OF THE PROTANDROUS ANEMONEFISH, AMPHIPRION CLARKII(Endocrinology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
- Thermal Diffusivity along X-Axis of Periodically Poled Mg-Doped Near-Stoichiometric LiTaO Device with Domain-Inverted Period of 8.0 m
- Comparison of in vitro vitellogenin synthesis among different nonylphenol products using primary cultures of tilapia hepatocytes