Selective Measurement of Hepatic Triglyceride Lipase and Lipoprotein Lipase in Rat Postheparin Plasma with Pentachlorophenol and Dichlorodiphenyltrichloroethane(Biological)
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概要
- 論文の詳細を見る
Postheparin plasma lipolytic activity consists of hepatic triglyceride Jipase(H-TGL) and lipoprotein lipase(LPL) activities. The effect of chlorinated pesticides, pentachlorophenol(PCP) and 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), on these lipase activities in rat postheparin plasma was examined. PCP completely inactivated H-TGL but did not change LPL activity. On the other hand, DDT completely inactivated LPL but did not change H-TGL activity. By utilizing these specific inhibitions, a procedure for selective measurement of H-TGL and LPL in postheparin plasma of young and old rats, with and without diabetes, was developed. The values of H-TGL and LPL activity obtained by this method were in good agreement with those obtained by immunochemical methods.
- 社団法人日本薬学会の論文
- 1987-07-25
著者
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田中 光也
School Of Pharmaceutical Sciences Toho University
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中内 瑞夫
School of Pharmaceutical Science, Toho University
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金木 弘之
Department of Hygienic Chemistry, School of Pharmaceutical Science, Toho University
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中内 瑞夫
Department of Hygienic Chemistry, School of Pharmaceutical Science, Toho University
-
田中 光也
Department of Hygienic Chemistry, School of Pharmaceutical Science, Toho University
-
金木 弘之
School Of Pharmaceutical Sciences Toho University
-
中内 瑞夫
School Of Pharmaceutical Science Toho University
関連論文
- Isolation and Identification of Self-Transfer Products Formed by Guinea Pig Liver β-Mannosidase(Organic,Chemical)
- Kinetic Study on the Binding of 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane to Rhizopus delemar C-Lipase : Rate Constants and the Effect of Slow Addition of the Ligand on Complex Formation
- Tryptophan Residues Involved in the Binding of Chlorinated Pesticides by Rhizopus delemar C-Lipase : Isolation of Tryptophan-Containing Peptides
- Modification of Tryptophan Residues on Rhizopus delemar C-Lipase Binding Chlorinated Pesticide by 2-Hydroxy-5-nitrobenzylation
- Interaction of Rhizopus delemar Lipase with 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane and Structurally Related Pesticides : Importance of 1 : 1 Pesticide-Lipase Complexes
- Selective Measurement of Hepatic Triglyceride Lipase and Lipoprotein Lipase in Rat Postheparin Plasma with Pentachlorophenol and Dichlorodiphenyltrichloroethane(Biological)
- Purification and Kinetic Properties of Guinea Pig Liver β-Mannosidase
- Adsorption of Some β-Glycosidases on N-(g-Aminohexanoyl)-β-D-glycosylamine-agarose
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