Antifungal Effect of Acrylic Resin Containing Apatite-coated TiO_2 Photocatalyst

概要

論文の詳細を見る
The purpose of this study was to develop an acrylic resin with antifungal properties by leveraging the photocatalytic activity of apatite-coated titanium dioxide (Ap-TiO_2). Candida albicans was used for antifungal activity assay of the specimen plates under ultraviolet A (UVA) with a black light source. Statistically significant decreases in cell viability in acrylic resins containing 5 wt% and 10 wt% Ap-TiO_2 were observed after irradiation for two, four, and six hours (P<0.01), when compared to the control. As for the flexural strength and modulus values of acrylic resins mixed with Ap-TiO_2 and TiO_2 particles, they varied before and after irradiation. Among the tested specimens, a 5 wt% content of Ap-TiO_2 in acrylic resin exceeded the requirements of ISO 1567. It was thus suggested that acrylic resin containing 5 wt% Ap-TiO_2 could exert antifungal effects on C. albicans, while at the same time maintain adequate mechanical properties for clinical use.