Terpenoid-Related Metabolites from a Formosan Soft Coral Nephthea chabrolii
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概要
- 論文の詳細を見る
Two new sesquiterpenoidal natural products chabrolidiones A and B (1 and 2), two _<18> terpenoid-related carboxylic acids, ketochabrolic acid (3) and isoketochabrolic acid (4), and one naphthoquinone derivative chabrolonaphthoquinone C (5), along with two known compounds (+)-aristolone (6) and teuhetenone A (7) were isolated from a Formosan soft coral Nephthea chabrolii. The structures of the new metabolites were determined on the basis of extensive spectroscopic analysis and by comparison of NMR data with those of related metabolites. Metabolite 1 has been synthesized previously, but was isolated for the first time from natural sources. Cytotoxic activity of metabolites 1-3 and 5-7 against a limited panel of cancer cell lines is also described.
- 公益社団法人日本薬学会の論文
- 2007-04-01
著者
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Sheu Jyh-Horng
Department of Marine Biotechnology and Resources, National Sun Yat-sen University
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Wu Yang-Chang
Graduate Institute of Natural Products, Kaohsiung Medical University
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HUANG Chiung-Yao
Department of Marine Biotechnology and Resources, National Sun Yat-sen University
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SU Jui-Hsin
Department of Biological Science and Technology, Meiho Institute of Technology
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HSU Chi-Hsin
Department of Marine Biotechnology and Resources, National Sun Yat-sen University
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Sheu Jyh-horng
Department Of Biological Science And Technology Meiho Institute Of Technology
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SUNG Ping-Jyun
National Museum of Marine Biology and Aquarium
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DAI Chang-Feng
Institute of Oceanography, National Taiwan University
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Dai Chang-feng
Institute Of Oceanography National Taiwan University
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Sheu J‐h
National Sun Yat‐sen Univ. Kaoshiung Twn
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Huang Chiung-yao
Department Of Marine Biotechnology And Resources National Sun Yat-sen University
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Hsu Chi-hsin
Department Of Marine Biotechnology And Resources National Sun Yat-sen University
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HUANG Hsin-Hui
Department of Marine Biotechnology and Resources, National Sun Yat-sen University
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Sung Ping-jyun
Graduate Institute Of Marine Biotechnology Department Of Life Science And Graduate Institute Of Biot
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Chung Hsu-ming
Dep. Of Marine Biotechnology And Resources National Sun Yat-sen Univ.
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Wu Yang-chang
Graduate Inst. Of Integrated Medicine Coll. Of Chinese Medicine China Medical Univ.
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Wu Yang-chang
Graduate Institute Of Integrated Medicine College Of Chinese Medicine China Medical University
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Wu Yang-chang
Graduate Inst. Of Integrated Medicine China Medical Univ.
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Huang Ho-Cheng
Department of Marine Biotechnology and Resources, National Sun Yat-sen University
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Sung Ping-Jyun
National Museum of Marine Biology & Aquarium (NMMBA)
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Su Jui-Hsin
Department of Biological Science and Technology, Mei-Ho Institute of Technology
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