511 SiO_2基板上に自己組織化するpoly(dA)・poly(dT) DNAの固着構造解析(J01-3 計算生体力学におけるマルチスケール・マルチフィジックス問題(3),J01 計算生体力学におけるマルチスケール・マルチフィジックス問題)

概要

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In recent years, the drastic improvement is required for the microfabrication technology of the novel semiconductor devices based on bionanotechnology. In the present research, we use the 50 base pairs poly (dA)・poly (dT) DNA as the electroconductive materials, and aim to obtain the basic design data of the nano-wiring technology. The effects of the DNA solution concentration and of a chemical surface treatment on the configuration of the self-organized network of DNA adhered on (100) SiO_2 substrate are experimentally investigated by the atomic force microscopy. Furthermore, we develop the simple DNA-substrate interaction model for ab initio calculation, and estimate quantitatively the local adhesion characteristics on the SiO_2 of DNA.
一般社団法人日本機械学会の論文
2005-09-18