Identification Tests of Aristolochic Acid in Crude Drugs by Reversed-Phase TLC/Scanning Densitometry
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概要
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We performed identification tests of aristolochic acid in Xixin, Mutong, Muxiang, and Fangji by reversed-phase TLC/scanning densitometry using aristolochic acid I as a marker compound. The developing solvents used were: I) acetonitrile/methanol/water mixture solution (3:1:1) and II) 2-butanone/methanol/sodium sulfate(1→20) mixture solution (2:1:1). The Rf value of aristolochic acid I was 0.54 using the I system and 0.57 using the II system. The maximum absorption wavelengths of aristolochic acid I observed by scanning densitometry were 254 and 325nm.
- 公益社団法人日本薬学会の論文
- 2006-02-01
著者
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MATSUMOTO Hiroshi
Aichi Prefectural Institute of Public Health
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Ohno Tsutomu
Aichi Prefectural Institute Of Public Health
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MIKAMI Eiichi
Aichi Prefectural Institute of Public Health
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Kawaguchi Naoki
Faculty of Pharmacy, Meijo University
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Matsumoto H
Department Of Electronics And Bioinformatics Science And Technology Meiji University
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Kawaguchi Naoki
Faculty Of Pharmacy Meijo University
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