A Protective Function of the Calcium Binding Protein S100A4 in Rat Hepatic Injury Due to Carbon Tetrachloride(International Symposium of Maxillofacial & Oral Regenerative Biology in OKAYAMA 2005)
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概要
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F The role of the S100A4 in rat hepatocites was clarified by measuring detailed changes in serum ALT values and intracellular Ca^<2+> after CCl_4 administration. In this study, we further showed that the calcium binding protein S100A4 might be a protein signal involved in the response to protect cells against CCl_4 intoxication. S100A4 mRNA expression levels abruptly increased to a high level in normal liver at 1 day after CCl_4 administration, and then gradually reduced to the control level by day 3. This change is the opposite to that of intracellular Ca^<2+>.
- 硬組織再生生物学会の論文
著者
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Taira Zenei
Faculty of Pharmaceutical Sciences, Tokushima Bunri University
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Taira Zenei
Faculty Of Pharmaceutical Sciences The University Of Tokushima:faculty Of Home Economics Shikoku Wom
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Ueda Yukari
Faculty Of Pharmaceutical Sciences Tokushima Bunri University
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Shiraishi Maya
Faculty Of Pharmaceutical Sciences Tokushima Bunri University
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Inui Yuka
Faculty of Pharmaceutical Sciences, Tokushima Bunri University
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Inui Yuka
Faculty Of Pharmaceutical Sciences Tokushima Bunri University
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