Clinicopathologic correlation of microsatellite instability with tri/tetranucleotide repeats in sporadic epithelial ovarian cancer
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概要
- 論文の詳細を見る
To determine how microsatellite instability (MSI) is related to clinicopathologic characteristics of epithelial ovarian cancer, we investigated MSI frequency on mono-, di-, tri-, and tetranucleotide repeats in 52 sporadic ovarian cancers. Thirty (57.7%) cases exhibited MSI in at least one of those loci. In the endometrioid adenocarcinomas (EA), MSI was observed in loci containing mono- and dinucleotide repeats. However, in the serous adenocarcinomas (SA) and the clear-cell carcinoma (CC), MSI was mainly observed in the loci with tri- and tetranucleotide repeats. Our results suggest that MSI in mono- and dinucleotide repeats is associated with EA and tri- and tetranucleotide repeats is associated with SA and CC.
- 近畿大学の論文
著者
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NAKAI Hidekatsu
Department of Obstetrics and Gynecology, Kinki University School of Medicine
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HOSHIAI Hiroshi
Department of Obstetrics and Gynecology, Kinki University School of Medicine
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WATANABE Yoh
Department of Obstetrics and Gynecology, Kinki University School of Medicine
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Hoshiai H
Department Of Obstetrics And Gynecology Kinki University School Of Medicine
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Watanabe Yoh
Kinki Univ. School Of Medicine Osaka Jpn
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Watanabe Yoh
Department Of Obstetrics And Gynecology Kinki University School Of Medicine
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Ueda Haruhiko
Department of Obstetrics and Gynecology, Kinki University School of Medicine
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Hoshiai Hiroshi
Department Of Obstetrics And Gynaecology Kinki University School Of Medicine
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Ueda Haruhiko
Department Of Obstetrics And Gynecology Kinki University School Of Medicine
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Nakai Hidekatsu
Department Of Obstetrics And Gynecology Kinki University School Of Medicine
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Hoshiai Hiroshi
Department Of Obstetric And Gynecology Kinki University Faculty Of Medicine
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Hoshiai Hiroshi
Department Of Obstetricts And Gynecology Kinki University Faculty Of Medicine
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