Synthesis and Peptidyl-Prolyl Isomerase Inhibitory Activity of Quinoxalines as Ligands of Cyclophilin A
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概要
- 論文の詳細を見る
In search of small molecule compounds as the ligands of cyclophilin A, a series of quinoxalines were prepared, and their K_d values of cyclophilin A and IC_<50> values for peptidyl-prolyl isomerase activity of cyclophilin A were tested. The results suggest that some quinoxalines are promising ligands of cyclophilin A.
- 公益社団法人日本薬学会の論文
- 2006-03-01
著者
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HE Xuchang
Shanghai Institute of Materia Medica, Chinese Academy of Sciences
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SHEN Xu
Shanghai Institute of Materia Medica, Chinese Academy of Sciences
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BAI Donglu
Shanghai Institute of Materia Medica, Chinese Academy of Sciences
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Shen Xu
Drug Discovery And Design Center State Key Laboratory Of Drug Research Shanghai Institute Of Materia
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Chen Jing
Dep. Of Cardiology Renmin Hospital Of Wuhan Univ.
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Chen Jing
Drug Discovery And Design Center State Key Laboratory Of Drug Research Shanghai Institute Of Materia
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Wang Feng
Shenzhen Inst. Of Xiangya Biomedicine
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He Xuchang
Shanghai Institute Of Materia Medica Chinese Academy Of Sciences
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Bai Donglu
中華人民共和国
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Bai Donglu
Shanghai Institute Of Materia Medica Chinese Academy Of Sciences
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WANG Feng
Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy o
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CHEN Jing
Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy o
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LIU Xuejun
Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy o
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JIANG Hualiang
Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy o
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Liu Xuejun
Shanghai Institute Of Materia Medica Shanghai Institutes For Biological Sciences Chinese Academy Of
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Jiang Hualiang
Drug Discovery And Design Center State Key Laboratory Of Drug Research Shanghai Institute Of Materia
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Liu Xuejun
Shanghai Institute Of Materia Medica Shanghai Institutes For Biological Sciences Chinese Academy Of
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