Immunology of the Human Immunodeficiency Virus Infection

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概要

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• From the beginning of the AIDS epidemy it was realized, that the immune system is the major target of the disease. After isolation of the ethiological agent-named the human immunodeficiency virusis became clear that there is a dual relationship between the immune system and HIV, i.e. HIV attaques the immune system and the immune system attaques the HIV. The present communication gives a brief rewiev of both aspects of the HIV infection. It is emphasised that both aspects of the relationship have inherent complexities illustrated on the one hand by the findings that the immunodeficiency cannot be explained solely by the established pathogenetic mechanism of lysis of the CD4+ T lymphocytes with ultimate depletion of the cells, and on the other hand by the fact that the virus manage to establish itself as a relentlessly progresing infection in seemingly all infected humans in spite of a vigorous anti-HIV directed immune response.

• 東海大学の論文
• 1990-03-08

著者

• Dickmeiss Ebbe

  Department Of Clinical Immunology State University Hospital (rigshospitalet)

関連論文

• Cytotoxic T Cell activity after HLA-mismatch Bone Marrow Transplantation
• Immunephenotyping of T Lymphocytes from Patients after Allogeneic Bone Marrow Transplantation
• Immunodeficiency after Allogeneic Bone Marrow Transplantation in Man : The Role of Antigen Presenting Cells
• Immunology of the Human Immunodeficiency Virus Infection
• The Immunodeficiency After Allogeneic Bone Marrow Transplantation in Man : Role of Cytokines

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