Immunephenotyping of T Lymphocytes from Patients after Allogeneic Bone Marrow Transplantation

スポンサーリンク

概要

• 論文の詳細を見る

• The relative distribution of T cell subsets as defined by MABs was analyzed in PBMCs from 56 patients with various hematologic diseases. The percentage of PBMCs expressing the CD5 antigen revealed normal values shortly after transplantation. In most patients lymphocytes expressing CD8 were found in high proportion and CD4 in a low percentage. This resulted in a low CD4/CD8 ratio compared with that of lymphocytes from normal controls. In the course of time, a trend toward normalization was observed for all parameters investigated, however the kinetics of the recovery showed a marked heterogeneity. Nevertheless, we found a statistical correlation between the CD4+cell count and the PHA transformation response. This could however, not be shown in ConA and PWM stimulated proliferation. No other correlation was found between any lymphocyte phenotype, as defined by MABs, and proliferative responses in vitro.

• 東海大学の論文

著者

• Moller J

  Department Of Internal Medicine B University Hospital In Copenhagen At Ferderiksberg

• Jacobsen Niels

  Department Of Internal Medicine B University Hospital In Copenhagen At Frederiksberg:department Of H

• Jacobsen N

  Department Of Internal Medicine B University Hospital In Copenhagen At Frederiksberg:department Of H

• MφLLER Jarl

  Department of Internal Medicine B, University Hospital in Copenhagen at Ferderiksberg

• DICKMEISS Ebbe

  Department of Clinical Immunology, University Hospital Rigshospitalet

• SVEJGAARD Arne

  Department of Clinical Immunology, University Hospital Rigshospitalet

• Mφller Jarl

  Department Of Internal Medicine B University Hospital In Copenhagen At Ferderiksberg

• Dickmeiss E

  Department Of Clinical Immunology University Hospital Rigshospitalet

• Dickmeiss Ebbe

  Department Of Clinical Immunology State University Hospital (rigshospitalet)

• Svejgaard A

  Department Of Clinical Immunology University Hospital Rigshospitalet

• Jacobsen Niels

  Department Of Clinical Immunology University Hospital Rigshospitalet

関連論文

• Cytotoxic T Cell activity after HLA-mismatch Bone Marrow Transplantation
• Immunephenotyping of T Lymphocytes from Patients after Allogeneic Bone Marrow Transplantation
• Immunodeficiency after Allogeneic Bone Marrow Transplantation in Man : The Role of Antigen Presenting Cells
• Intravenous Hyperimmune Globulin Prophylaxis against Cytomegalovirus Interstitial Pneumonitis after Allogenic Bone Marrow Transplantation
• Immunology of the Human Immunodeficiency Virus Infection
• The Immunodeficiency After Allogeneic Bone Marrow Transplantation in Man : Role of Cytokines

スポンサーリンク